Antibody Characterization Service

Service Features:

  • Real-time BLI-based (Bio-layer Interferometry) biophysical characterization of polyclonal and monoclonal antibody affinities (Kd) for antigen

  • Quantification of  Kon and Koff rates for many antibody/antigen pairs underlying their dissociation constants

  • Epitope binning based upon antibody binding to non-overlapping epitopes

  • Antibody screening to reveal appropriate biophysical profiles for specific applications

Figure 1. Association and dissociation of IFN to a surface-immobilized antibody using varying concentrations of IFN to determine antibody affinity. The raw data are shown in blue and the model response in red.

         

IFN Binding to and Disassociation from a Surface-Immobilized Monoclonal Antibody Evaluated by BLI

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Please include any project requirements or preferences including, for example, (1) number of samples, (2) sample matrix type(s), (3) volume of each sample, and (4) preferred number of replicates (e.g. singlet, duplicate, triplicate).

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