EMD Millipore Single Molecule Counting (SMCxPRO & Erenna) Assay Services: Ultra-Sensitive Cytokine Testing
Key Features offered by Single Molecule Counting Technology on SMCxPRO and Erenna Platforms:
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Enables sub-pg/ml sensitivity for accurate measurement of low abundance biomarkers in serum, plasma or other complex matrices
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Requires minimal sample dilution with a 4-Log+ dynamic range
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Provides high precision and reproducible data
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Extensive analyte menu of over 30 different cytokine assays covering several disease areas
For a detailed overview of the Single Molecule Counting cytokine detection technology, click here.
For additional information, check out PBL's Ultra-Sensitive Immunoassay Poster and Ultra-Sensitive Cytokine Detection Service Flyer.
Figure 1. Median levels of IL-1b (Interleukin 1 Beta) in Plasma Samples (Heparin, Citrate and EDTA)
Available Singulex Immunoassays on Single Molecule Counting (SMCxPRO® & Erenna®) Platforms:
*The Representative Functional LLOQ is the assay’s Representative Analytical LLOQ corrected for a Recommended Sample Dilution Factor specific to each assay. Both the Representative Calibration Range and Functional LLOQ are often lot-specific.
|
Assay [Catalog No.] |
Species | Matrix | Representative Calibration Range | Representative Functional LLOQ | Datasheet |
|---|---|---|---|---|---|
| Aβ-40 [03-0145-00] Amyloid Beta 1-40 High Sensitivity Assay Kit |
Human, Mouse, Rat |
CSF, Plasma |
2.93 – 3,000 pg/mL |
CSF: 117.2 pg/mL P: 23.44 pg/mL |
Datasheet |
| Aβ-42 [03-0146-00] Amyloid Beta 1-42 High Sensitivity Assay Kit |
Human, Mouse, Rat |
CSF, Plasma |
0.24 – 250 pg/mL |
CSF: 19.6 pg/mL P: 3.92 pg/mL |
Datasheet |
| AKT1 (Ser473) [03-0100-01] Phospho AKT1 Assay Kit |
Human, Mouse, Rat |
Lysate |
1 – 1,000 pg/mL |
Dependent on Cell Line | Datasheet |
| AKT1 (Total) [03-0099-01] Total Phospho AKT1 Assay Kit |
Human, Mouse, Rat |
Lysate |
0.2 – 200 pg/mL |
Dependent on Cell Line | Datasheet |
| BDNF [03-0171-00] Brain-Derived Neurotrophic Factor High Sensitivity Assay Kit |
Human |
CSF, Plasma, Serum |
0.02 – 100 pg/mL |
CSF: 0.04 pg/mL P: 4 pg/mL S: 4 pg/mL |
Datasheet |
| cTnI [03-0092-00] Cardiac Troponin I Assay Kit |
Canine, Cynomolgus, Guinea Pig, Human, Rat |
Plasma, Serum |
0.17 – 600 pg/mL |
Not Given |
Datasheet |
| cTnI [03-0154-00] Cardiac Troponin I Assay Kit |
Canine, Cynomolgus, Guinea Pig, Human, Rat |
Plasma, Serum |
0.17 – 600 pg/mL |
0.69 pg/mL |
Datasheet |
| G-CSF [03-0047-00] Granulocyte Colony-Stimulating Factor Assay Kit |
Human |
Plasma |
0.02 – 20 pg/mL |
Not Given | Datasheet |
| GLP-1 (Active) [03-0024-03] Active Glucagon-Like Peptide 1 Assay Kit |
Canine, Human, Mouse, Rat |
Plasma |
0.05 – 50 pg/mL |
Not Given | Datasheet |
| GLP-1 (Total) [03-0025-06] Total Glucagon-Like Peptide 1 Assay Kit |
Canine, Human, Mouse, Rat |
Plasma |
0.2 – 200 pg/mL |
Not Given | Datasheet |
| Glucagon [03-0153-00] Glucagon High Sensitivity Assay Kit |
Human, Mouse, Rat |
Plasma |
0.2 – 200 pg/mL |
7.81 pg/mL | Datasheet |
| GM-CSF [03-0067-00] Granulocyte Macrophage Colony-Stimulating Factor Assay Kit |
Human |
Plasma |
0.005 – 5 pg/mL |
Not Given | Datasheet |
| IFN-γ [03-0049-00] Inteferon Gamma Assay Kit |
Human |
Plasma |
0.02 – 25 pg/mL |
Not Given | Datasheet |
| IL-1α [03-0072-00] Interleukin 1 Alpha Assay Kit |
Human |
Plasma, Serum |
0.1 – 100 pg/mL |
Not Given | Datasheet |
| IL-1α [03-0167-00] Interleukin 1 Alpha High Sensitivity Assay Kit |
Human |
Plasma, Serum |
0.06 – 60 pg/mL |
0.12 pg/mL | Datasheet |
| IL-1β [03-0028-00] Interleukin 1 Beta Assay Kit |
Human |
Plasma |
0.049 – 50 pg/mL |
Not Given | Datasheet |
| IL-1β [03-0160-00] Interleukin 1 Beta High Sensitivity Assay Kit |
Human |
Plasma, Serum |
0.05 – 50 pg/mL |
0.2 pg/mL | Datasheet |
| IL-2 [03-0051-00] Interleukin 2 Assay Kit |
Human |
Plasma, Serum |
0.05 – 50 pg/mL |
Not Given | Datasheet |
| IL-4 [03-0052-00] Interleukin 4 Assay Kit |
Human |
Plasma |
0.01 – 100 pg/mL |
Not Given | Datasheet |
| IL-4 [03-0161-00] Interleukin 4 High Sensitivity Assay Kit |
Human | Plasma, Serum |
0.01 – 100 pg/mL |
0.04 pg/mL | Datasheet |
| IL-5 [03-0053-00] Interleukin 5 Assay Kit |
Human | Plasma, Serum |
0.98 – 1,000 pg/mL |
Not Given | Datasheet |
| IL-5 [03-0168-00] Interleukin 5 High Sensitivity Assay Kit |
Human | Plasma, Serum |
0.01 – 50 pg/mL |
0.04 pg/mL | Datasheet |
| IL-6 [03-0089-01] Interleukin 6 Assay Kit |
Human | Plasma |
0.01 – 50 pg/mL |
Not Given | Datasheet |
| IL-6 [03-0155-00] Interleukin 6 High Sensitivity Assay Kit |
Human | Plasma, Serum |
0.01 – 50 pg/mL |
0.08 pg/mL | Datasheet |
| IL-7 [03-0094-00] Interleukin 7 Assay Kit |
Human | Plasma |
0.1 – 100 pg/mL |
Not Given | Datasheet |
| IL-8/CXCL-8 [03-0055-00] Interleukin 8 Assay Kit |
Human | Plasma |
0.24 – 250 pg/mL |
Not Given | Datasheet |
| IL-10 [03-0056-00] Interleukin 10 Assay Kit |
Human | Plasma |
0.17 – 400 pg/mL |
Not Given | Datasheet |
| IL-10 [03-0176-00] Interleukin 10 High Sensitivity Assay Kit |
Human | Plasma, Serum |
0.1 – 100 pg/mL |
0.1 pg/mL | Datasheet |
| IL-12 [03-0057-00] Interleukin 12 Assay Kit |
Human | Plasma, Serum |
0.01 – 12.5 pg/mL |
Not Given | Datasheet |
| IL-13 [03-0109-02] Interleukin 13 (v2) Assay Kit |
Human | Plasma, Serum |
0.02 – 100 pg/mL |
Not Given | Datasheet |
| IL-13 [03-0156-00] Interleukin 13 High Sensitivity Assay Kit |
Human | Plasma, Serum |
0.02 – 100 pg/mL |
0.04 pg/mL | Datasheet |
| IL-15 [03-0058-00] Interleukin 15 Assay Kit |
Human | Plasma, Serum |
0.02 – 25 pg/mL |
Not Given | Datasheet |
| IL-17A [03-0103-00] Interleukin 17A (v2) Assay Kit |
Human | Plasma, Serum |
0.01 – 20 pg/mL |
Not Given | Datasheet |
| IL-17A [03-0159-00] Interleukin 17A High Sensitivity Assay Kit |
Human | Plasma, Serum |
0.02 – 60 pg/mL |
0.06 pg/mL | Datasheet |
| IL-17A/F [03-0177-00] Interleukin 17A/F High Sensitivity Assay Kit |
Human | Plasma, Serum |
0.6 – 600 pg/mL |
4.68 pg/mL | Datasheet |
| IL-17A/F Heterodimer [03-0119-00] Interleukin 17A/F Heterodimer (v2) Assay Kit |
Human | Plasma, Serum |
0.3 – 300 pg/mL |
Not Given | Datasheet |
| IL-21 [03-0014-07] Interleukin 21 Assay Kit |
Human | Plasma, Serum |
0.11 – 250 pg/mL |
Not Given | Datasheet |
| IL-22 [03-0059-01] Interleukin 22 Assay Kit |
Human | Plasma |
0.1 – 100 pg/mL |
Not Given | Datasheet |
| IL-22 [03-0162-00] Interleukin 22 High Sensitivity Assay Kit |
Human | Plasma, Serum |
0.05 – 50 pg/mL |
0.4 pg/mL | Datasheet |
| IL-23 [03-0112-00] Interleukin 23 Assay Kit |
Human | Plasma, Serum |
0.1 – 100 pg/mL |
Not Given | Datasheet |
| IL-23 [03-0157-00] Interleukin 23 High Sensitivity Assay Kit |
Human | Plasma, Serum |
0.05 – 50 pg/mL |
0.1 pg/mL | Datasheet |
| KIM-1 [03-0118-00] Kidney Injury Molecule 1 Assay Kit |
Human | Plasma, Serum, Urine |
1 – 1,000 pg/mL |
Not Given | Datasheet |
| TNF-α [03-0088-00] Tumor Necrosis Factor Alpha Assay Kit |
Human | Plasma |
0.049 – 50 pg/mL |
Not Given | Datasheet |
| TNF-α [03-0163-00] Tumor Necrosis Factor Alpha High Sensitivity Assay Kit |
Human | Plasma, Serum |
0.05 – 50 pg/mL |
0.2 pg/mL | Datasheet |
| TNF-α [03-0108-00] Tumor Necrosis Factor Alpha Assay Kit |
Mouse | Serum |
0.05 – 50 pg/mL |
Not Given | Datasheet |
| VEGF [03-0068-00] Vascular Endothelial Growth Factor Assay Kit |
Human | Plasma |
0.1 – 100 pg/mL |
Not Given | Datasheet |
| VEGF-A [03-0180-00] Vascular Endothelial Growth Factor A High Sensitivity Assay Kit |
Human | Plasma, Serum |
0.1 – 100 pg/mL |
0.8 pg/mL | Datasheet |
PBL Assay Science's ultra-sensitive cytokine detection services are powered by MilliporeSigma's Single Molecule Counting technology in conjunction with robust microparticle (MP) based sandwich immunoassays that enables accurate, high-precision baseline quantification of low-abundance analytes at or below sub-picogram concentrations.
The background reduction methodology of this detection service extends the linear dynamic range to over 4 logs allowing scientists to measure biomarkers in many disease states at unprecedented levels. In addition to minimal sample dilution, robust and reproducible data make this detection service a great tool that can help scientists come to an increased understanding of analyte activities in biological responses.
Powered by SMCxPRO® & Erenna® Immunoassay Systems, EMD Millipore Inc., Burlington, MA, USA.
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