Assay Services

Meso Scale Discovery Assay Services: MSD-ECL Assays

       

Advantages of Meso Scale Discovery Assay Services:

 

  • Ability to target low analyte levels in small sample volumes empowered by the Meso Scale Discovery® Electrochemiluminesence (MSD-ECL) technology

Cell-Based Assay Services: Cytokine/Chemokine Bioactivity & Antiviral Assays

 

Cell-based assay tools are key to understanding cellular mechanisms in a biologically relevant context. PBL offers a targeted portfolio of cell-based assay services to provide you with the most relevant information and facilitate advancement of your research.

 

Whatever your cell-based study needs, PBL will work with you to determine the most suitable assay program to meet your goals. PBL's services team is a trusted partner of midsize and major biotech and pharma companies worldwide.

 

Additional PBL Assay Services

PBL Assay Science has the ability to offer additional services, including but not limited to Assay Design & Development, Assay Optimization, Technology Transfer, and Consulting. Our approach is to tailor the service to meet your specific project needs, not a one-size-fits-all attitude.

 

Simoa Assay Services: Ultra-Sensitive Biomarker Testing

       

Advantages of Simoa Assay Services:

  • Utilizing Single Molecule Array technology to deliver femtogram per milliliter (fg/ml) level sensitivity for measurement of low-abundance biomarkers in serum, plasma and other matrices

EMD Millipore (Singulex) Erenna Assay Services: Ultra-Sensitive Cytokine Testing

       

Key Features of EMD Millipore (Singulex) Erenna Assay Services:

  • Cytokine analysis utilizing Single Molecule Counting (SMC) technology enables sub-pg/ml sensitivity for accurate measurement of low abundance biomarkers in serum or plasma

Reagent Development Services: Proteins, Cytokines & Antibodies

 

PBL's reagent development services offer customized production of cytokines, interferons, antibodies, and other proteins.

 

Antibody Characterization Service

       

Service Features:

  • SPR-based biophysical characterization of polyclonal and monoclonal antibody affinities (Kd) for antigen

  • Quantification of  Kon and Koff rates for many antibody/antigen pairs underlying their dissociation constants

Cytokine Secretion Assays

       

Service Features:

  • Accurate measurement of the ability of a sample to induce cytokine expression in and release from cell lines or isolated donor cells

Single Analyte & Multiplex ELISA Services

       

Service Features:

  • ELISA services to perform cytokine and interferon (IFN) measurement

  • Available in single analyte and customizable multiplex formats

Proliferation & Anti-Proliferation Assays

       

Service Features:

  • Growth inhibition, growth promotion, and cytotoxicity assay services to evaluate cytokine and other modulator activities

  • Utilizes cell lines sensitive to IFNs or other growth-modulating cytokines

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