Human Cytokine and IFN Multiplex Assays

Why take advantage of PBL Multiplexes?

 

  • Unique Human Type I, II, and III IFN & Cytokine panels allow rapid profiling of immune and inflammatory cytokine expression levels
  • Robust technology for accurate analyte quantification in serum samples
  • Cost-effective ELISA platform amenable to customization to include your analytes of interest
  • Ready-to-run multiplex kits or testing services to obtain results more quickly

Email us to find out how PBL's Mulriplex Kits and

Testing Services can help your project.

 

 

VeriPlex Human Cytokine 16-Plex ELISA Kit (51510-1)

 

Panel:

IFN-α, IFN-β, IFN-γ, IFN-λ1, 2,& 3

IL-1α, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12p70, IL-13, IL-15, IL-17, & IL-23

TNF-α

 

Matrix Compatibility: Serum, Plasma, & Tissue Culture Media

 

Assay Range: 2.86 log with LLOD and LLOQ in the low pg/ml range

 

VeriKine Human Cytokine 16-Plex ELISA normal human serum spike-recovery

 

 

VeriPlex Human IFN 9-Plex ELISA Kit (51500-1)

 

Panel:

IFN-α, IFN-β, IFN-ω, IFN-γ, IFN-λ1, 2, & 3

IL-1α, IL-6

IP-10, TNF-α

 

Martix Compatibility: Serum, Plasma, & Tissue Culture Media

 

Assay Range: 2.86 log with LLOD and LLOQ in the low pg/ml range

 

VeriPlex Human IFN 9-Plex ELISA

 

 

Increased interferon (IFN) levels are a hallmark of many disease, as members of this family of cytokines are sentinels in the innate immune response. High levels of Type I (IFN-Alpha & IFN-Beta) and Type III (IFN-Lambda) IFNs are produced upon host detection of nucleic acids during viral infections and some autoimmune diseases. Increases in Type II (IFN-Gamma) generally correlate with immune responses to intracellular pathogens and tumors.
 

In addition to IFNs, other cytokines also are indicators of nascent immune responses. Interleukins (IL-1Alpha, IL-6) and TNF-Alpha are endogenous pyrogens that are produced to raise the body temperature and help eliminate infections. Interleukins 6, and 8 (IL-6, IL-8) were increased in plasma from patients with ulcerative colitis, whereas IFN-Gamma levels were decreased.

 

Simultaneously analyzing the concentrations of multiple cytokines in a sample, and drawing correlations with expression profiles or disease severity, may allow a global understanding of ongoing immune responses in diseases ranging from cancer to autoimmunity.

 

 

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