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Full Product Name: Human Interleukin-28A/Interferon Lambda 2, Human Cell-Expressed (HCE)
Catalog No. | Pack Size | Price | Quantity |
---|---|---|---|
11720-1 |
≥ 1 x 105 units |
$285.00 |
Formulation | Supplied frozen in phosphate buffered saline (PBS) containing 0.1% bovine serum albumin (BSA) |
Molecular Weight | 19.8 kDa |
Source | Recombinant DNA expressed in human cells |
Purity | Greater than 95% as determined by ion exchange, hydrophobic interaction and/or size exclusion chromatography Endotoxin level < 1 EU/μg |
Bioactivity | Measured in cytopathic effect inhibition assay on human lung carcinoma cell line A549 with encephalomyocarditis virus (EMCV), EC50 ~1 U/ml |
Storage | For retention of full activity store at -70°C or below and avoid repeated freeze/thaw cycles |
Synonyms | Hu-IL-28A; Hu-IFN-λ2 |
Accession Number | NP_742150.1 |
Interferon lambda 1 (IL-29), interferon lambda 2 (IL-28A) and interferon lambda 3 (IL-28B) are recently identified members of the IL-10 family, which have antiviral activity similar to type I interferons. They mediate this activity through a heterodimeric receptor complex that is composed of the IL-10 receptor β (IL-10 Rβ) and a novel IL-28 receptor α (IL-28 Rα, also known as IFN-λ R1). Engagement of this receptor leads to Jak-STAT signaling and gene expression. Many of the effects of interferon lambda on cells overlap that of Type I interferon. Unlike the type I interferon receptor which is on virtually all cells, the type III receptor is limited in its expression1. Interferon lambda 1 encodes a 181 AA mature protein which is 67% and 69% identical with interferon lambda 2 and interferon lambda 3, respectively.
References:
Catalog No. | Description | Pack Size | Price | Quantity |
---|---|---|---|---|
11725-1 |
Human IL-29/IFN Lambda 1, HCE |
≥ 1 x 105 units |
$285.00 |
|
11730-1 |
Human IL-28B/IFN Lambda 3, HCE |
≥ 1 x 105 units |
$285.00 |
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PBL Assay Science offers scientists a comprehensive range of assay kits, interferons, cytokines, growth factors and antibodies. Our high quality products provide consistent, reliable performance and are suitable for use in a range of research applications.
Quick Search
PBL’s improved site search function is defaulted to an exact match.
Search Term Results |
|
IFN beta |
All interferon beta products and related technical information (e.g. technical notes) |
Human IFN beta |
All human interferon products related technical information (e.g. technical notes) |
IL-2 |
All products contain the term “IL-2”, including IL-23 |
IL 2 |
All products contain the term “IL 2”, including IL-23 |
Erythropoietin |
All EPO products and technical information |
Eryth |
All EPO products and technical information |
The results are displayed in best match products grouped in the following product category filters:
Each filter contains sub-categories for further narrowing of your search results
Other web content such as technical notes that contain the Search Term can be displayed by checking the box next to the corresponding filter on the left side of the Search Results Page.