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General Information, Educational Materials and FAQs
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Resources: Application Notes, Posters, Protocols/Guides, References, Technical Hints & Tips
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Product Literature: Brochures/Flyers, Citations and White Papers
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Literature Request
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Lot Specific CoA Search
General Information
Education
General Interferon
- New RNA Interference: Interferon response can act as an adjuvant, an off-target effect, or a confounding factor
- Introduction to Interferon
- Introduction to Interferon Alpha Cytopathic Effect Assay
- Measuring Interferon Alpha Level
- Interferon Beta and Multiple Sclerosis
- Human Interferon Alpha Nomenclature
- Mouse Interferon Alpha Nomenclature
Frequently Asked Questions (FAQs)
Click here for FAQs on IFNs, Cytokines, Antibodies and Assay Kits.
Posters
A collection of educational posters on IFN and Cytokine related research topics.
Resources
Application Notes
Proteins and Antibodies:
- A Comparison of the Binding of IFN Alpha Subtypes to isolated IFNAR1 and IFNAR2 with Activity in Antiviral and Antiproliferative Assays
- Binding and Neutralization of Monoclonal Antibodies to Human IFN Alpha Subtypes
- Polyclonal Antibodies Neutralization of Human IFN Alpha
Assay Kits:
- Multiplex Profiling of Cytokines released by A549 Human Lung Epithelial Cells after Infection with Encephalomyocarditis Virus and Vesicular Stomatitis Virus
- Differential Biological Activities of E.coli Produced Murine IFN Alpha Proteins on B16-F10 Cells
- IFN Gamma Activity and ELISA Detection Comparison
- Human IFN Alpha ELISA Plasma Matrix Study
- VeriKine Cynomolgus/Rhesus IFN Alpha Serum ELISA Performance Evaluation
- Use of iLite Human IFN Alpha Kit and an Anti-IFNAR2 Neutralizing Antibody in Rapid Activity Determination of IFNs Secreted from poly I:C Stimulated A549 Cells
PBL Posters & Presentations
- An Approach to Characterizing Ultra-Sensitive Immunoassays. Case Studies with IL-17F, IL-17A, IL-1 beta and Other Analytes
- 2015 PBL Assay Solutions
- Chronic and Acute Markers of Interferon Stimulation
- Validation of a Highly Sensitive Immunoassay for the Quantitation of IFN Beta in Autoimmune Sera
- Serum soluble IFNAR2 levels in autoimmune diseases suggest that chronic IFN signaling leads to elevated levels of sIFNAR2
- Performance Characterization of Ultra-Sensitive Cytokine Detection Immunoassays
- IFN beta therapy increases concentration of soluble IFN alpha/beta receptor in Multiple Sclerosis patient serum
- Multiplex Profiling of Cytokines released by A549 Human Lung Epithelial Cells after Infection with Encephalomyocarditis Virus and Vesicular Stomatitis Virus
- Antiviral Activity of Cytokines
- A Comparison of the Binding of IFN Alpha Subtypes to isolated IFNAR1 and IFNAR2 with Activity in Antiviral and Antiproliferative Assays
- The Relative Antiviral Activity of Human IFN Alphas on Primate Cell Lines, and Mouse Alpha IFNs on Hamster and Rat Cell Lines
- Neutralization Activity of the Vaccinia Virus B18R protein against the Human IFN Alpha protein family
- Synergy of Interferons and Bortezomib: Advantages of Combination
- Biological Characterization of Feline IFN-Nu: A New Member of the Type I IFN Family
- Binding and Neutralization of Monoclonal Antibodies to Human IFN Alpha Subtypes
- Differential Biological Activities of E.coli Produced Murine IFN Alpha Proteins on B16-F-10 Cells
- Biological Activities and Detection of Cynomolgus IFN-Alpha Subtypes
Protocols and Guides
A list of general protocols for experimental and troubleshooting reference.
- General Spike-Recovery Protocol for ELISA
- General Protocol for Human Interferon Alpha Cytopathic Effect Assay
- General Procedure for Cell Surface Staining
- General Procedure for Intra-Cellular Staining
- Flow Cytometry for IFNAR2 on JURKAT cells
- Flow Cytometry for IFNAR2 on Human PBMC
References
Please click here to see a list of selected publications on of and related topics.
Tips, Tools and Troubleshooting
- A Cost-Effective Antibody Cocktail For Broad Neutralization of Human Type I IFN
- VeriKine Mouse IFN Alpha ELISA Kit Use with Tissue Homogenates
- Antibodies against Human IFN Alpha Subtype Specificities Comparison Chart
- General Protein Handling Guide
- Human IFN Alpha ELISA Subtype Specificities Comparison Chart
- ELISA Troubleshooting Guide
- ELISA Data Analysis with Four-Parameter Curve Fit
- Importance of ELISA Standard Curve
Product Literature
Brochures/Flyers
PDFs presenting background information, product/services capabilities, graphic illustrations, representative data and related product lists.
Assay Services:
- Assay Services Brochure
- Ultra-Sensitive Biomarker Quantification Assay Service
- Ultra-Sensitive Cytokine Detection Assay Service
- MSD-ECL Protein Detection Service
Human Kits:
- High Sensitivity Human IFN Alpha All Subtype ELISA
- High Sensitivity Human IFN Beta Serum ELISA
- VeriPlex Human Cytokine 16-Plex ELISA
- VeriPlex Human IFN 9-Plex ELISA
Mouse Kits:
Non-Human Kit:
Reagents:
- Neutralizing Antibodies
- Anti-Human ISG 15, Clone 2.1
- Human Cell-Expressed Hu IFN Lambda Proteins
- Universal Type I IFN
- Anti-Human IFN Alpha/Beta Receptor 1 (IFNAR1) Antibodies
- Mouse IFN Beta, mammalian
- Mouse IFN Alpha 4, mammalian
- NEW Rat IFN Alpha 1 and IFN Alpha 14, mammalian
Product Lines:
White Papers
Articles describing the utility and application of PBL's products.
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