Human Type 1 IFN Neutralizing Antibody Mixture

Product Features: 
  • Mixture of monoclonal and polyclonal antibodies directed against human Type 1 Interferons (IFNs) and Type 1 Receptor Subunit 2 (IFNAR2)
  • Effectively neutralizes biological activity of human IFN-alpha, IFN-beta, IFN-omega, IFN-kappa, and IFN-epsilon
  • Improves neutralization of multiple Type I IFNs often found in complex samples by employing a broadly neutralizing custom antibody cocktail
  • Unconjugated

Ordering

Catalog No. Pack Size Price Quantity
39000-1

0.2 ml

$570.00

Specifications

Formulation Supplied frozen in phosphate-buffered saline (PBS)
Purification A combination of Protein G affinity chromatography and other conventional chromatographical methods.
Endotoxin level < 1 EU/μg
Bioactivity Encephalomyocarditis Virus (EMCV) was used to challenge A549 cells which were incubated with a constant concentration of the antibody mixture and the titrated interferon.
Specificity Blocks biological activity of human Type I interferons (alpha, beta, omega, kappa, epsilon)
No cross reactivity observed with the following human interferons: gamma, lambda 1, lambda 2, lambda 3; or mouse interferons: alpha, beta, gamma
Storage For retention of full activity store at -70°C or below and avoid repeated freeze/thaw cycles
Synonyms Type I interferon, Type I IFN, Neutralizing, Neutralization, Type I Interferon Receptor, Antibody Cocktail

Tech Info / Data

Tested Applications:

  • Neutralization

Citations

Representative Neutralization Curves

Human Type I IFN Neutralization in A549 Cells

Representative neutralization curves of Human Type I IFN Neutralizing Antibody Mixture (Catalog No. 39000) (diluted 1:50) to human interferon alpha, beta, and omega. In this assay, A549 cells (human lung carcinoma) were incubated with the antibody mixture and titrated interferon, followed by challenging with encephalomyocarditis virus (EMCV).

Related Products

Catalog No. Description Pack Size Price Quantity
12185-1 C12R Mouse Interferon Alpha Decoy Receptor

10 μg

$275.00
12185-2 C12R Mouse Interferon Alpha Decoy Receptor

100 μg

$925.00

Find your lot-specific Certificate of Analysis here!

Finding the right biomarker detection service to meet your project needs just got easier...

Sign up for our email list to be kept up-to-date on the latest product releases and company news!

Go to top