Human Type I IFN Neutralizing Antibody Mixture

Catalog Number: 39000

Highly recommended unconjugated mixture of MAbs and PAbs directed against human Type I IFN receptor and several Type I IFNs. Effectively neutralizes biological activity of human IFN-Alpha, IFN-Beta, IFN-Omega, IFN-Kappa, and IFN-Epsilon.

$711.00
Pack Size
Human Type I IFN Neutralization in A549 Cells.

Human Type I IFN Neutralization in A549 Cells.

Product Info

Specificity

Blocks biological activity of human Type I interferons (alpha, beta, omega, kappa, epsilon)


No cross-reactivity observed with the following:

  • Human IFN-Gamma, lFN-Lambda 1, IFN-Lambda 2, IFN-Lambda 3, Mouse IFN-Alpha, IFN-Beta, IFN-Gamma
Tested Application
  • Neutralization

 

Improves neutralization of multiple Type I IFNs often found in complex samples by employing a broadly neutralizing custom antibody cocktail.

Documentation

Certificate of Analysis (CoA) and Safety Data Sheet (SDS)

FormulationSupplied frozen in phosphate-buffered saline (PBS)
PurificationA combination of Protein G affinity chromatography and other conventional chromatographical methods.
Endotoxin level < 1 EU/μg
BioactivityEncephalomyocarditis Virus (EMCV) was used to challenge A549 cells which were incubated with a constant concentration of the antibody mixture and the titrated interferon.
StorageFor retention of full activity store at -70°C or below and avoid repeated freeze/thaw cycles
SynonymsType I interferon, Type I IFN, Neutralizing, Neutralization, Type I Interferon Receptor, Antibody Cocktail