NULISA Assay Services
- Ultrasensitive automated proteomic platform enables protein biomarker quantitation into the attomolar (sub-femtogram/ml) range with the Alamar Biosciences ARGO™ HT System
- Flexible plexing technology spans single-plex, low-plex, and high-plex formats. From one targeted analyte to hundreds of proteins, in a single ultrasensitive proteomics workflow
- Close to 12-log dynamic range quantifies low- and high-abundance proteins in the same run, without dilution optimization or platform-switching
- Low sample-volume requirements allow hundreds of analytes to be quantified from one small sample, preserving limited or irreplaceable material such as biobanked or longitudinal samples
See below for representative data
PBL builds each NULISA solution around the specific needs of your study. Our scientists begin with your biology, biomarker target list, concentration range, sample type, and timeline to recommend the right assay and readout method. When an existing assay doesn't cover your target, we can develop a custom NULISA-based immunoassay on the Alamar Biosciences ARGO™ HT System.
Backed by 35 years of assay development and manufacturing experience, the PBL Assay Science team guides assay selection, design, and data interpretation. We don't simply process samples—our Subject Matter Experts guide your projects from beginning to end.
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NULISA Platform Features
Dual capture-and-release purification strips non-specifically bind material from the antibody-DNA complex before quantification, eliminating background that limits sensitivity in single-purification immunoassay formats
- Dual readout options match turnaround and coverage to study needs: qPCR for single-plex and low-plex assays, and next-generation sequencing for high-plex panels
- Absolute quantification reports validated targets in fg/ml - pg/ml rather than relative signal units, enabling direct comparison across cohorts, sites, and time points
- Sub-10% CV across replicates supports reproducible, analysis-ready data for longitudinal and multi-site studies
Powered by Alamar Biosciences ARGO™ HT System, Fremont, CA, USA
