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Full Product Name: VeriKine Human Interferon Alpha Multi-Subtype ELISA Kit
Looking for a TCM compatible All Subtype ELISA? Check out our NEW 41135 kit!
Catalog No. | Pack Size | Price | Quantity |
---|---|---|---|
41105-2 |
5 x 96-well plate |
$2,650.00 |
|
41105-1 |
1 x 96-well plate |
$635.00 |
Materials Provided:
Tips, Tools and Troubleshooting:
The VeriKine Human IFN-α Multi-Subtype ELISA kit is specifically formulated to detect 14 out of 15 identified human IFN-α subtypes/alleles in media using a sandwich immunoassay. They are: IFN-αA, IFN-α2, IFN-αD, IFN-αB2, IFN-αC, IFN-αG, IFN-αH, IFN-αI, IFN-αJ1, IFN-αK, IFN-α1, IFN-α4a, IFN-α4b, and IFN-αWA. The kit is based on an ELISA with anti-detection antibody conjugated to horseradish peroxidase (HRP). Tetramethyl-benzidine (TMB) is the substrate. The assay is based on the international reference standard for human interferon alpha (Hu-IFN-α) provided by the National Institutes of Health.
Interferons (IFNs) are a family of mammalian cytokines initially characterized by their ability to inhibit viral infection. Generation of type I IFNs occurs downstream of a multitude of immunologic stimuli and can be either an indicator of host defense or an indicator of autoimmunity. In addition to their antiviral properties, IFNs have also been shown to exhibit anti-proliferative, immunomodulatory, and many other activities.
In humans, Interferon Alpha (IFN-alpha) is a family comprised of more than 12 homologous protein subtypes that exhibit diverse biologic activities. This group of proteins are greater than 85% homologous by amino acid sequence. Numerous individual human IFN-α subtypes have been identified; many display different properties. It remains unclear why there are multiple IFN-α subtypes. A variety of studies suggested they possess overlapping but also unique sets of biological activities. At least one subtype is used as a therapeutic, as a readout of drug efficacy in clinical trials, and as a marker of pathology in human clinical and preclinical studies. Elucidating the functional significances of various IFN-alpha subtypes can lead to further refinement of current interferon based therapeutic applications.
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Assay Range: 12.5 - 500 pg/ml
Catalog No. | Description | Pack Size | Price | Quantity |
---|---|---|---|---|
41135-1 |
VeriKine-HS Human Interferon Alpha All Subtype TCM ELISA Kit Compatibility: Tissue Culture Media Assay Range: 1.95-125 pg/ml |
1 x 96-well plate |
$445.00 |
|
41115-1 |
VeriKine-HS Human Interferon Alpha All Subtype ELISA Kit Compatibility: Serum, Plasma, Tissue Culture Media Assay Range: 1.95-125 pg/ml |
1 x 96-well plate |
$695.00 |
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PBL Assay Science offers scientists a comprehensive range of assay kits, interferons, cytokines, growth factors and antibodies. Our high quality products provide consistent, reliable performance and are suitable for use in a range of research applications.
Quick Search
PBL’s improved site search function is defaulted to an exact match.
Search Term Results |
|
IFN beta |
All interferon beta products and related technical information (e.g. technical notes) |
Human IFN beta |
All human interferon products related technical information (e.g. technical notes) |
IL-2 |
All products contain the term “IL-2”, including IL-23 |
IL 2 |
All products contain the term “IL 2”, including IL-23 |
Erythropoietin |
All EPO products and technical information |
Eryth |
All EPO products and technical information |
The results are displayed in best match products grouped in the following product category filters:
Each filter contains sub-categories for further narrowing of your search results
Other web content such as technical notes that contain the Search Term can be displayed by checking the box next to the corresponding filter on the left side of the Search Results Page.