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Mouse IFN-Beta, Mammalian, Carrier-Free

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Mouse IFN-Beta, Mammalian, Carrier-Free

Catalog Number: 12410

Mammalian expressed recombinant Mouse IFN-Beta protein supplied carrier-free to minimize possible immunogenic reactions by host animal in in vivo studies. This protein has an authentic sequence with no tag. 

$755.00

Pack Size
Product Info

Application
  • in vivo injection studies
Bioactivity Measured using a cytopathic effect inhibition assay on Mouse (L929) cells with EMCV. 
EC50 for IFN Beta is ~ 2.5 U/ml

Specifications

Formulation Supplied frozen in 20mM Sodium Phosphate pH 6.4; 300mM NaCl; 5% Glycerol
Molecular Weight 19.6 kDa
Source Gene obtained from mouse DNA expressed in mammalian cells
Purity > 95% by SDS-PAGE stained by Coomassie Blue
Endotoxin level < 1 EU/μg
Storage For retention of full activity store at -70°C or below and avoid repeated freeze/thaw cycles
Synonyms Mouse Beta Interferon, Mouse IFN Beta, Mouse IFNB, Mouse Type I IFN beta, Mouse Fibroblast IFN, Mouse Fibroblast Interferon, Mouse Beta IFN, Mouse Type I Interferon Beta
Accession Number K00020

Citations

5 Citations

 

  1. Li, N. et al., (2023), "STING controls opioidinduced itch and chronic itch via spinal tank-binding kinase 1-dependent type I interferon response in mice", J. Neuroinflammation, 20(1):101, PMID: 37122031, DOI: 10.1186/s12974-023-02783-0 (link)

  2. Baran, M. et. al.,  (2023), "PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection", Cell Rep.,  42(4):112341, PMID: 37018072, DOI: 10.1016/j.celrep.2023.112341 (link)

  3. Ka, N., et al.,  (2021), "IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer", Cell Reports, 37:110138, DOI: 10.1016/j.celrep.2021.110138 (link)

  4. Thaney, Victoria, et al. (2017). IFN-beta Protects Neurons From Damage in a Murine Model of HIV-1 Associated Brain Injury. Scientific Reports, 16 pgs. PMID: 28425451. (link)

  5. Taylor, Katherine, et al. (2014). Age-Dependent Myeloid Dendritic Cell Responses Mediate Resistance to La Crosse Virus-Induced Neurological Disease. JVI, 10 pgs. PMID: 25008929. (link)

Documentation

Certificate of Analysis (CoA), Safety Data Sheet (SDS), and Product Flyer
12410-1 CoA

12410-1 Certificate of Analysis (CoA)

12410 SDS

12410 Safety Data Sheet

12405/12410 Flyer

12405/12410 Flyer