Mouse IFN-Beta, Mammalian, Carrier-Free
Catalog Number: 12410
Mammalian expressed recombinant Mouse IFN-Beta protein supplied carrier-free to minimize possible immunogenic reactions by host animal in in vivo studies. This protein has an authentic sequence with no tag.
Measured using a cytopathic effect inhibition assay on Mouse (L929) cells with EMCV.
EC50 for IFN Beta is ~ 2.5 U/ml
|Formulation||Supplied frozen in 20mM Sodium Phosphate pH 6.4; 300mM NaCl; 5% Glycerol|
|Molecular Weight||19.6 kDa|
|Source||Gene obtained from mouse DNA expressed in mammalian cells|
|Purity||> 95% by SDS-PAGE stained by Coomassie Blue
Endotoxin level < 1 EU/μg
|Storage||For retention of full activity store at -70°C or below and avoid repeated freeze/thaw cycles|
|Synonyms||Mouse Beta Interferon, Mouse IFN Beta, Mouse IFNB, Mouse Type I IFN beta, Mouse Fibroblast IFN, Mouse Fibroblast Interferon, Mouse Beta IFN, Mouse Type I Interferon Beta|
- Ka, N., et al., (2021), "IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer", Cell Reports, 37:110138, DOI: 10.1016/j.celrep.2021.110138 (link)
- Thaney, Victoria, et al. (2017). IFN-beta Protects Neurons From Damage in a Murine Model of HIV-1 Associated Brain Injury. Scientific Reports, 16 pgs. PMID: 28425451. (link)
- Taylor, Katherine, et al. (2014). Age-Dependent Myeloid Dendritic Cell Responses Mediate Resistance to La Crosse Virus-Induced Neurological Disease. JVI, 10 pgs. PMID: 25008929. (link)