Mouse IFN-Beta, Mammalian, Carrier-Free
Catalog Number: 12410
Mammalian expressed recombinant Mouse IFN-Beta protein supplied carrier-free to minimize possible immunogenic reactions by host animal in in vivo studies. This protein has an authentic sequence with no tag.
$755.00
Product Info
Application Bioactivity Measured using a cytopathic effect inhibition assay on Mouse (L929) cells with EMCV.
EC50 for IFN Beta is ~ 2.5 U/ml
Specifications
| Formulation | Supplied frozen in 20mM Sodium Phosphate pH 6.4; 300mM NaCl; 5% Glycerol |
|---|---|
| Molecular Weight | 19.6 kDa |
| Source | Gene obtained from mouse DNA expressed in mammalian cells |
| Purity | > 95% by SDS-PAGE stained by Coomassie Blue Endotoxin level < 1 EU/μg |
| Storage | For retention of full activity store at -70°C or below and avoid repeated freeze/thaw cycles |
| Synonyms | Mouse Beta Interferon, Mouse IFN Beta, Mouse IFNB, Mouse Type I IFN beta, Mouse Fibroblast IFN, Mouse Fibroblast Interferon, Mouse Beta IFN, Mouse Type I Interferon Beta |
| Accession Number | K00020 |
Citations
5 Citations
- Li, N. et al., (2023), "STING controls opioidinduced itch and chronic itch via spinal tank-binding kinase 1-dependent type I interferon response in mice", J. Neuroinflammation, 20(1):101, PMID: 37122031, DOI: 10.1186/s12974-023-02783-0 (link)
- Baran, M. et. al., (2023), "PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection", Cell Rep., 42(4):112341, PMID: 37018072, DOI: 10.1016/j.celrep.2023.112341 (link)
- Ka, N., et al., (2021), "IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer", Cell Reports, 37:110138, DOI: 10.1016/j.celrep.2021.110138 (link)
- Thaney, Victoria, et al. (2017). IFN-beta Protects Neurons From Damage in a Murine Model of HIV-1 Associated Brain Injury. Scientific Reports, 16 pgs. PMID: 28425451. (link)
- Taylor, Katherine, et al. (2014). Age-Dependent Myeloid Dendritic Cell Responses Mediate Resistance to La Crosse Virus-Induced Neurological Disease. JVI, 10 pgs. PMID: 25008929. (link)