Anti-Mouse IFN Beta Antibody, Clone RMMB-1 (MAb)

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Product Features: 
  • Rat monoclonal antibody against Mouse IFN Beta
  • Suitable for use in Direct Binding ELISAs
  • Unconjugated
  • Binds to mouse interferon beta (weakly neutralizes)

Ordering

Catalog No. Pack Size Price Quantity
22400-1

250 μg

 $375.00

Specifications

Formulation Supplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA)
Antigen Mouse interferon beta
Isotype IgG2ak
Host Species Rat
Purity > 95% by SDS-PAGE stained by Coomassie Blue
Endotoxin level < 1 EU/μg
Bioactivity Measured by neutralization of interferon in cytopathic effect inhibition assay
Specificity Weakly neutralizes mouse IFN-beta, but not recommended for neutralization assays (for this application products 32400-1 or 32401-1 are recommended) ; binds to mouse IFN-beta
Storage For retention of full activity store at -20°C or below and avoid repeated freeze/thaw cycles
Antigen Synonyms Mouse IFN Beta, Mouse Beta Interferon, Mouse IFNB, Mouse Type I IFN beta, Mouse Fibroblast IFN, Mouse Fibroblast Interferon, Mouse Beta IFN, Mouse Type I Interferon Beta
Clone RMMB-1

Tech Info / Data

Tested Applications:

  • Direct Binding ELISA

Note: PBL has not tested the use of this product in western blot, flow cytometry, immunoprecipitation or immunohistochemistry.

Citations

8 Citations:

  1. Sivick, Kelsey, et al. (2018). Magnitude of Therapeutic STING Activation Determines CD8+ T Cell-Mediated Anti-tumor Immunity. Cell Reports, 18 pgs. PMID: 30540940. (link)

  2. Francica, Brian, et al. (2018). TNFα and Radioresistant Stromal Cells Are Essential for Therapeutic Efficacy of Cyclic Dinucleotide STING Agonists in Nonimmunogenic Tumors. Cancer Immunology Research, 25 pgs. PMID: 29472271. (link)

  3. von Buttlar, Heiner, et al. (2014). Identification of Toll-Like Receptor 9 as Parapoxvirus Ovis-Sensing Receptor in Plasmacytoid Dendritic Cells. PLOS One, 8 pgs. PMID: 25171368. (link)

  4. Sutherland, DB, et al. (2011). Evaluating vaccinia virus cytokine co-expression in TLR GKO mice. Immunology and Cell Biology. PMID: 21173782. (link)

  5. Horkheimer, Ian, et al. (2009). Induction of type I IFN is required for overcoming tumor-specific T-cell tolerance after stem cell transplantation. Blood Journal, 19 pgs. PMID: 19279333. (link)

  6. Roth-Cross, Jessica, et al. (2008). Murine Coronavirus Mouse Hepatitis Virus is Recognized by MDA5 and Induces Type I Interferon in Brain Macrophages/Microglia. JVI, 11 pgs. PMID: 18667505. (link)

  7. Qin, Lizeng, et al. (2007). Effects of Type I Interferons on the Adjuvant Properties of Plasmid Granulocyte-Macrophage Colony-Stimulating Factor In Vivo. JVI, 8 pgs. PMID: 17652387. (link)

  8. Zhu, Jiangao, et al. (2007). Innate Immune Response to Adenoviral Vectors Is Mediated by both Toll-Like Receptor-Dependent and -Independent Pathways. JVI, 11 pgs. PMID: 17229689. (link)

Documentation

Direct Binding ELISA

22400-1 Anti-Mouse IFN Beta Monoclonal Antibody Direct Binding ELISA Curve

Representative binding curve of antibody to recombinant Mouse IFN Beta (circle) and to 1% BSA/PBS (square) in a Direct Binding ELISA.

Related Products

Catalog No. Description Pack Size Price Quantity
12405-1 Mouse Interferon Beta, mammalian

1 x 105 units

 $270.00
32400-1 Anti-Mouse Interferon Beta, Rabbit Serum (PAb)

2 x 104 units

 $365.00
32401-1 Anti-Mouse Interferon Beta, Rabbit IgG, Protein A purified (PAb)

2 x 104 units

 $425.00

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