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Anti-Mouse IFN-Beta, Clone RMMB-1 (MAb)

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Anti-Mouse IFN-Beta, Clone RMMB-1 (MAb)

Catalog Number: 22400

This unconjugated Rat monoclonal antibody against Mouse Interferon Beta is suitable for use in Direct Binding ELISAs and binds to mouse interferon beta (weakly neutralizes).


Pack Size
Product Info

Specificity Weakly neutralizes mouse IFN-Beta, but not recommended for neutralization assays (for this application product 32401-1 is recommended); binds to mouse IFN-Beta
Tested Application
  • Direct Binding ELISA


Note: PBL has not tested the use of this product in Western Blot (WB), flow cytometry, immunoprecipitation or immunohistochemistry.


Formulation Supplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA)
Antigen Mouse interferon beta
Isotype IgG2ak
Host Species Rat
Purity > 95% by SDS-PAGE stained by Coomassie Blue
Endotoxin level < 1 EU/μg
Bioactivity Measured by neutralization of interferon in cytopathic effect inhibition assay
Storage For retention of full activity store at -20°C or below and avoid repeated freeze/thaw cycles
Antigen Synonyms Mouse IFN Beta, Mouse Beta Interferon, Mouse IFNB, Mouse Type I IFN beta, Mouse Fibroblast IFN, Mouse Fibroblast Interferon, Mouse Beta IFN, Mouse Type I Interferon Beta
Clone RMMB-1


10 Citations


  1. Silveira Prudente, A. et al., (2024), "Microglial STING activation alleviates nerve injury-induced neuropathic pain in male but not female mice", Brain Behav Immun., PMID: 38190983, DOI: 10.1016/j.bbi.2024.01.003 (link)

  2. Heidegger, S., et al., (2023), "Targeting nucleic acid sensors in tumor cells to reprogram biogenesis and RNA cargo of extracellular vesicles for T cell-mediated cancer immunotherapy", Cell Rep Med., 101171, PMID: 37657445, DOI: 10.1016/j.xcrm.2023.101171 (link)

  3. Sivick, Kelsey, et al. (2018). Magnitude of Therapeutic STING Activation Determines CD8+ T Cell-Mediated Anti-tumor Immunity. Cell Reports, 18 pgs. PMID: 30540940. (link)

  4. Francica, Brian, et al. (2018). TNFα and Radioresistant Stromal Cells Are Essential for Therapeutic Efficacy of Cyclic Dinucleotide STING Agonists in Nonimmunogenic Tumors. Cancer Immunology Research, 25 pgs. PMID: 29472271. (link)

  5. von Buttlar, Heiner, et al. (2014). Identification of Toll-Like Receptor 9 as Parapoxvirus Ovis-Sensing Receptor in Plasmacytoid Dendritic Cells. PLOS One, 8 pgs. PMID: 25171368. (link)

  6. Sutherland, DB, et al. (2011). Evaluating vaccinia virus cytokine co-expression in TLR GKO mice. Immunology and Cell Biology. PMID: 21173782. (link)

  7. Horkheimer, Ian, et al. (2009). Induction of type I IFN is required for overcoming tumor-specific T-cell tolerance after stem cell transplantation. Blood Journal, 19 pgs. PMID: 19279333. (link)

  8. Roth-Cross, Jessica, et al. (2008). Murine Coronavirus Mouse Hepatitis Virus is Recognized by MDA5 and Induces Type I Interferon in Brain Macrophages/Microglia. JVI, 11 pgs. PMID: 18667505. (link)

  9. Qin, Lizeng, et al. (2007). Effects of Type I Interferons on the Adjuvant Properties of Plasmid Granulocyte-Macrophage Colony-Stimulating Factor In Vivo. JVI, 8 pgs. PMID: 17652387. (link)

  10. Zhu, Jiangao, et al. (2007). Innate Immune Response to Adenoviral Vectors Is Mediated by both Toll-Like Receptor-Dependent and -Independent Pathways. JVI, 11 pgs. PMID: 17229689. (link)


Certificate of Analysis (CoA) and Safety Data Sheet (SDS)
22400-1 CoA

22400-1 Certificate of Analysis

22400 SDS

22400 Safety Data Sheet