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Anti-Mouse IFN-Beta, Clone RMMB-1 (MAb)

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Anti-Mouse IFN-Beta, Clone RMMB-1 (MAb)

Catalog Number: 22400

This unconjugated Rat monoclonal antibody against Mouse Interferon Beta is suitable for use in Direct Binding ELISAs and binds to mouse interferon beta (weakly neutralizes).

$405.00

Pack Size
Product Info

Specificity Weakly neutralizes mouse IFN-Beta, but not recommended for neutralization assays (for this application product 32401-1 is recommended); binds to mouse IFN-Beta
Tested Application
  • Direct Binding ELISA

 

Note: PBL has not tested the use of this product in Western Blot (WB), flow cytometry, immunoprecipitation or immunohistochemistry.

Specifications

Formulation Supplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA)
Antigen Mouse interferon beta
Isotype IgG2ak
Host Species Rat
Purity > 95% by SDS-PAGE stained by Coomassie Blue
Endotoxin level < 1 EU/μg
Bioactivity Measured by neutralization of interferon in cytopathic effect inhibition assay
Storage For retention of full activity store at -20°C or below and avoid repeated freeze/thaw cycles
Antigen Synonyms Mouse IFN Beta, Mouse Beta Interferon, Mouse IFNB, Mouse Type I IFN beta, Mouse Fibroblast IFN, Mouse Fibroblast Interferon, Mouse Beta IFN, Mouse Type I Interferon Beta
Clone RMMB-1

Citations

8 Citations

 

  1. Sivick, Kelsey, et al. (2018). Magnitude of Therapeutic STING Activation Determines CD8+ T Cell-Mediated Anti-tumor Immunity. Cell Reports, 18 pgs. PMID: 30540940. (link)

  2. Francica, Brian, et al. (2018). TNFα and Radioresistant Stromal Cells Are Essential for Therapeutic Efficacy of Cyclic Dinucleotide STING Agonists in Nonimmunogenic Tumors. Cancer Immunology Research, 25 pgs. PMID: 29472271. (link)

  3. von Buttlar, Heiner, et al. (2014). Identification of Toll-Like Receptor 9 as Parapoxvirus Ovis-Sensing Receptor in Plasmacytoid Dendritic Cells. PLOS One, 8 pgs. PMID: 25171368. (link)

  4. Sutherland, DB, et al. (2011). Evaluating vaccinia virus cytokine co-expression in TLR GKO mice. Immunology and Cell Biology. PMID: 21173782. (link)

  5. Horkheimer, Ian, et al. (2009). Induction of type I IFN is required for overcoming tumor-specific T-cell tolerance after stem cell transplantation. Blood Journal, 19 pgs. PMID: 19279333. (link)

  6. Roth-Cross, Jessica, et al. (2008). Murine Coronavirus Mouse Hepatitis Virus is Recognized by MDA5 and Induces Type I Interferon in Brain Macrophages/Microglia. JVI, 11 pgs. PMID: 18667505. (link)

  7. Qin, Lizeng, et al. (2007). Effects of Type I Interferons on the Adjuvant Properties of Plasmid Granulocyte-Macrophage Colony-Stimulating Factor In Vivo. JVI, 8 pgs. PMID: 17652387. (link)

  8. Zhu, Jiangao, et al. (2007). Innate Immune Response to Adenoviral Vectors Is Mediated by both Toll-Like Receptor-Dependent and -Independent Pathways. JVI, 11 pgs. PMID: 17229689. (link)

Documentation

Certificate of Analysis (CoA) and Safety Data Sheet (SDS)
22400-1 CoA

22400-1 Certificate of Analysis

22400 SDS

22400 Safety Data Sheet