Scientific
Insights

Why p-tau217? Alzheimer’s disease (AD) remains one of the most challenging neurodegenerative disorders to diagnose and treat effectively. As researchers have tried to untangle the complexities of the disease, including the accumulation of amyloid…

Neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, Multiple Sclerosis (MS), and Frontotemporal Dementia, impact over 50 million people worldwide ( 1). By 2040, these diseases are projected to become the world's second…

When it comes to ELISA kits used for the detection of protein biomarkers, one observation we have made at PBL Assay Science—over and over again—is that not all assays are created equal. From our 30+ years of experience designing and manufacturing…

When it comes to biomarkers testing, choosing a contract research organization (CRO) is not just about finding capacity. It is about finding alignment. In an era where biotech funding is tight and project timelines are under scrutiny, the CRO you…

A healthy economy needs both large and small businesses. Big companies bring resources and consistency that are hard to match at a smaller scale, but small businesses bring something different: they can adapt quickly, they often know their craft…

Summary: This article examines how Type I IFNs can support or undermine peripheral immune tolerance by shaping regulatory T cells, epigenetic programs, and thymus selection, and why dysregulated signaling is linked to autoimmunity. Introduction The…