Single Molecule Counting (SMCxPRO & Erenna) Assay Services: Sensitive Cytokine Testing

MilliporeSigma Single Molecule Counting (SMCxPRO® & Erenna®)

• Cytokine analysis utilizing Single Molecule Counting technology enables sub-pg/ml sensitivity for accurate measurement of low abundance biomarkers in normal or disease sera/plasma

• Minimal sample dilution requirement with 4-Log+ dynamic range

• High precision cytokine immunoassays provide reproducible data

• Extensive analyte menu of over 40 different cytokine assays covering several disease areas including IFN-γ, IL-1a, IL-1b, IL-4, IL-6, IL-8, IL-10, IL-13, IL-15, IL-17A, IL-17F, IL-17 heterodimer, IL-23, GLP-1, and TNF-α

PBL Assay Science's ultra-sensitive cytokine detection services are powered by MilliporeSigma's Single Molecule Counting technology in conjunction with robust microparticle (MP) based sandwich immunoassays that enables accurate, high-precision baseline quantification of low-abundance analytes at or below sub-picogram concentrations.

The ability to accurately measure low-abundance analytes present in complex matrices is essential for the profiling and characterization of cytokines and other biomarker analytes. Employing proprietary single molecule counting technology with robust microparticle-based SMCxPRO® & Erenna® immunoassays, PBL’s cytokine detection services can provide scientists with sub-pg/ml level measurements of low-abundance analytes in healthy or disease sera and plasma.

The background reduction methodology of this detection service extends the linear dynamic range to over 4 logs allowing scientists to measure biomarkers in many disease states at unprecedented levels. In addition to minimal sample dilution, robust and reproducible data make this detection service a great tool that can help scientists come to an increased understanding of analyte activities in biological responses.