Assay
Development

Cell-based assay development service offered, but not limited to:

• Custom cytopathic effect, anti-proliferation, and growth promotion assays
• Development of reporter gene systems or identification of cell lines to monitor activity of the compound of interest
• Neutralization of bioactivity by antibodies which is relevant to identification of bioactive monoclonal antibodies (MAbs) and monitoring of immunogeneicity

Custom immunoassays and ELISAs to support:

• Pharmacokinetic and pharmacodynamic studies
• Toxicity and immunogenicity studies
• Direct, sandwich, or competitive ELISA assay development

• Specificity and cross-reactivity assessment
• Analytic and dynamic range optimization
• Reduction of matrix effects (serum, plasma, tissue culture media)
• Reduction of inter- and intra-assay variability
• Standard calibration
• Assay stability assessment
• Protocol optimization