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Full Product Name: VeriKine-HS Pig Interferon Alpha ELISA Kit
Catalog No. | Pack Size | Price | Quantity |
---|---|---|---|
47100-1 |
1 x 96-well plate |
$610.00 |
Materials Provided:
The Verikine-HS Pig IFN-α ELISA kit will enable determination of IFN-α levels in serum, plasma, and tissue culture media. As such, it should prove an important tool in virology, immunomodulation, and immunotoxicology studies conducted in pigs.
Interferons (IFNs) are a group of cytokines which exhibit pleiotropic activities that play major roles in both innate and adaptive immunity. Type I IFNs consist of at least one IFN-β gene and protein as well as multiple IFN-α genes and proteins in most vertebrate species. IFN-α expression and secretion is primarily induced by signaling events processed through pattern recognition receptors such as the Toll-like and RIG-I like receptors (TLR and RLR, respectively). While IFN-α can be produced by most cell types, strong evidence suggests that plasmacytoid dendritic cells are a major source of IFN-α in vivo. Following expression and secretion, IFN-α binds to a hetero-dimeric receptor chain consisting of IFNAR1 and IFNAR2 subunits on proximal and distal cell surfaces. Receptor binding promotes a signal transduction cascade consisting of components of the JAK-STAT signaling pathway. Hundreds of genes are regulated subsequent to binding of the IFNAR receptor subunits to IFN-α, thus leading to the antiviral, anti-proliferative, and immunomodulatory activities of the cytokine.
The domestic pig (Sus scrofa or Sus domestica) is an important livestock animal. As such, diseases that affect livestock are frequently studied in this animal. Furthermore, it is also a significant model of human infectious disease. One of the hallmarks of viral and other infectious diseases is the production of interferon. A number of studies have already highlighted the importance of the IFN system in pigs.
References: (For additional references, please reference the protocol.)
Catalog No. | Description | Pack Size | Price | Quantity |
---|---|---|---|---|
17105-1 |
Porcine Interferon Alpha |
1 x 105 units |
$395.00 |
|
27100-1 |
Anti-Pig Interferon Alpha, Clone K9 (MAb) |
500 μg |
$360.00 |
|
27105-1 |
Anti-Pig Interferon Alpha, Clone F17 (MAb) |
500 μg |
$360.00 |
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PBL Assay Science offers scientists a comprehensive range of assay kits, interferons, cytokines, growth factors and antibodies. Our high quality products provide consistent, reliable performance and are suitable for use in a range of research applications.
Quick Search
PBL’s improved site search function is defaulted to an exact match.
Search Term Results |
|
IFN beta |
All interferon beta products and related technical information (e.g. technical notes) |
Human IFN beta |
All human interferon products related technical information (e.g. technical notes) |
IL-2 |
All products contain the term “IL-2”, including IL-23 |
IL 2 |
All products contain the term “IL 2”, including IL-23 |
Erythropoietin |
All EPO products and technical information |
Eryth |
All EPO products and technical information |
The results are displayed in best match products grouped in the following product category filters:
Each filter contains sub-categories for further narrowing of your search results
Other web content such as technical notes that contain the Search Term can be displayed by checking the box next to the corresponding filter on the left side of the Search Results Page.