Human IFN Beta 1b, E.coli

Home / Products / Proteins / Interferons / Human IFN Proteins / Human IFN Beta 1b, E.coli
Product Features: 
  • Human IFN Beta 1b, E.coli, recombinant protein
  • Type I IFN
  • Single non-glycosylated polypeptide chain, serine replace cysteine at residue 17

Ordering

Catalog No. Pack Size Price Quantity
11420-1

1 x 105 units

 $230.00

Specifications

Formulation Supplied frozen with a carrier protein
Molecular Weight 20 kDa
Source cDNA obtained from human fibroblast interferon beta mRNA expressed in E.coli
Purity > 95% by SDS-PAGE stained by Coomassie Blue
Endotoxin level < 1 EU/μg
Bioactivity Measured using a cytopathic inhibition assay on human lung carcinoma cell line A549 with encephalomyocarditis virus (EMCV). EC50 for IFN beta 1b in this assay is ~ 1 U/ml
Synonyms Human IFNB, Human Beta Interferon, Human IFN Beta 1b, Human Interferon beta 1b, Human Type I Interferon Beta, Human IFN B
Storage For retention of full activity store at -70°C or below and avoid repeated freeze/thaw cycles
Accession Number V00534

Citations

5 Citations:

  1. Nair, Sajith, et al. (2016). Global Functional Profiling of Human Ubiquitome Identifies E3 Ubiquitin Ligase DCST1 as a Novel Negative Regulator of Type-I Interferon Signaling. Scientific Reports, 13 pgs. PMID: 27782195. (link)

  2. Novatt, Hilary, et al. (2016). Distinct Patterns of Expression of Transcription Factors in Response to Interferon-beta and Interferon-gamma-1. Journal of Interferon & Cytokine Research, 10 pgs. PMID: 27447339. (link)

  3. Ambjorn, Malene, et al. (2016). IFNB1/Interferon-beta-Induced Autophagy in MCF-7 Breast Cancer Cells Counteracts its Proapoptotic Function. Autophagy, 17 pgs. PMID: 23221969. (link)

  4. Lim, Efrem, et al. (2009). Simian Immunodeficiency Virus SIV_agm From African green Monkeys Does Not Antagonize Endogenous Levels of African Green Monkey Tetherin/BST-2. JVI, 9 pgs. PMID: 19726508. (link)

  5. Barr, Stephen, et al. (2008). The Interferon Response Inhibits HIV Particle Production by Induction of TRIM22. PLOS Pathogens, 11 pgs. PMID: 18389079. (link)

Documentation

Human IFN Beta 1b, E.coli Titration in A549

Titration of Human Interferon Beta 1b, E.coli in the A549 Cell Line

Related Products

Catalog No. Description Pack Size Price Quantity
41435-1 VeriKine-HS Human IFN Beta TCM ELISA Kit  new 
Compatibility: Tissue Culture Media
Assay Range: 2.34 - 150 pg/ml

1 x 96-well plate

 $450.00
11410-2 Human Interferon Beta 1a, mammalian, carrier-free

1 x 106 units

 $555.00
11415-1 Human Interferon Beta 1a, mammalian

1 x 105 units

 $330.00

Looking for a CoA?

Find your lot-specific Certificate of Analysis here!

Which service best suits your needs?

Finding the right biomarker detection service to meet your project needs just got easier...

Want to stay in touch?

Sign up for our email list to be kept up-to-date on the latest product releases and company news!

Go to top