Human IFN-Beta 1a, mammalian, carrier-free
Catalog Number: 11410
Useful for MS research studies, recombinant Human IFN-Beta 1a protein is expressed in CHO cells.
$620.00
Product Info
Supplied without a carrier protein and as a liquid to maintain higher specific activity.
Specifications
| Formulation | Supplied as a liquid without a carrier protein |
|---|---|
| Molecular Weight | ~ 23 kDa |
| Source | cDNA obtained from human fibroblast interferon beta 1a mRNA expressed in CHO cells |
| Purity | > 95% by SDS-PAGE stained by Coomassie Blue Endotoxin level < 1 EU/μg |
| Bioactivity | Measured using a cytopathic inhibition assay on human lung carcinoma cell line A549 with encephalomyocarditis virus (EMCV). EC50 for IFN beta 1a in this assay is ~1 U/ml |
| Storage | For retention of full activity store at 2-8°C. Further dilution of this product for long term storage is not recommended. |
| Synonyms | Human IFNB, Human Beta Interferon, Human IFN Beta 1a, Human Interferon beta 1a, Human Type I Interferon Beta, Human IFN B |
| Accession Number | V00534 |
Citations
20 Citations
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- Patel, Dhara, et al. (2012). High Throughout Screening for Small Molecule Enhancers of the Interferon Signaling Pathway to Drive Next-Generation Antiviral Drug Discovery. PLOS One, 12 pgs. PMID: 22574190. (link)
- Popugaeva, Elena, et al. (2012). Dobrava-Belgrade hantavirus from Germany shows receptor usage and innate immunity induction consistent with the pathogenicity of the virus in humans. PLOS One, 10 pgs. PMID: 22545121. (link)
- Witte, et al. (2009). Despite IFN-lambda receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: implications for therapeutic applications of these cytokines. Nature, 13 pgs. PMID: 19798076. (link)
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