Human IFN-Alpha H2 (Alpha 14)
Catalog Number: 11145
Human Interferon Alpha 14 recombinant protein expressed in E.coli.
Recombinant Human Interferon Alpha H2 (alpha 14) obtained from human leukocyte mRNA expressed in E.coli.
IFN alpha 14 is one of the many interferon alpha subtypes belonging to the Type I leukocyte IFN family. The Type I IFN family has antiviral, anti-proliferative, and natural killer cell activities.
- Expression induced by viral infection
- Encoding gene IFNA14
|Formulation||Supplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA)|
|Molecular Weight||19.7 kDa|
|Source||cDNA obtained from human leukocyte mRNA expressed in E.coli|
|Purity||> 95% by SDS-PAGE stained by Coomassie Blue|
|Bioactivity||Measured using a cytopathic inhibition assay on Bovine Kidney Cells (MDBK) with Vesicular Stomatis Virus (VSV); human lung carcinoma cell line A549 with encephalomyocarditis virus (EMCV)|
|Storage||For retention of full activity store at -70 ºC or below and avoid repeated freeze-thaw cycles|
Tech Info & Data
- A Comparison of the Binding of IFN-Alpha Subtypes to Isolated IFNAR1 and IFNAR2 with Activity in Antiviral and Antiproliferative Assays (link)
- Wilson, Timothy R, et al. (2012). Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature, 12 pgs. PMID: 22763448. (link)
- Kang, Dong-Chul, et al. (2004). Expression Analysis and Genomic Characterization of Human Melanoma Differentiation Associated Gene-5, mda-5: a Novel Type I Interferon-Responsive Apoptosis-Inducing Gene. Oncogene, 12 pgs. PMID: 14676839. (link)