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Human IFN-Alpha J1 (Alpha 7)

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Human IFN-Alpha J1 (Alpha 7)

Catalog Number: 11160

Human Interferon Alpha 7 recombinant protein expressed in E.coli.

$335.00

Pack Size
Product Info

Recombinant Human IFN-Alpha J1 (alpha 7) obtained from human leukocyte mRNA expressed in E.coli.

 

IFN-Alpha 7 is one of the many interferon alpha subtypes belonging to the Type I leukocyte IFN family.  The Type I IFN family has antiviral, anti-proliferative, and natural killer cell activities.

 

  • Expression is induced by viral infection
  • Encoding gene IFNA7

Specifications

Formulation Supplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA)
Molecular Weight 19.6 kDa
Source cDNA obtained from human leukocyte mRNA expressed in E.coli
Purity > 95% by SDS-PAGE stained by Coomassie Blue
Endotoxin level < 1 EU/mg
Bioactivity Measured using a cytopathic inhibition assay on Bovine Kidney Cells (MDBK) with Vesicular Stomatis Virus (VSV); human lung carcinoma cell line A549 with encephalomyocarditis virus (EMCV)
Storage For retention of full activity store at -70 ºC or below and avoid repeated freeze-thaw cycles
Synonyms Hu-IFN-α7
Accession Number X02960

Tech Info & Data

Application Note

 

  • A Comparison of the Binding of the Interferon Alpha Subtypes to Isolated IFNAR1 and IFNAR2 with Activity in Antiviral and Antiproliferative Assays (link)

Citations

3 Citations

 

  1. Wilson, Timothy R, et al. (2012). Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature, 12 pgs. PMID: 22763448. (link)

  2. Kang, Dong-Chul, et al. (2004). Expression Analysis and Genomic Characterization of Human Melanoma Differentiation Associated Gene-5, mda-5: a Novel Type I Interferon-Responsive Apoptosis-Inducing Gene. Oncogene, 12 pgs. PMID: 14676839. (link)

  3. Li, et al. (1990). Alpha-interferon structure and natural killer cell stimulatory activity. Cancer Research, 6 pgs. PMID: 2201435. (link)

Documentation

Certificate of Analysis (CoA) and Safety Data Sheet (SDS)
11160-1 CoA

11160-1 Certificate of Analysis (CoA)

11160 SDS

11160 Safety Data Sheet