iLite Human Type I Interferon Responsive Cells

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Product Features: 
  • Reporter gene cells for Human Type 1 Interferon (IFN) bioactivity measurement
  • Indirectly measure Neutralizing Antibodies (NAbs) to IFN alpha or IFN beta
  • Provided as assay ready frozen cells 
  • Cell line is highly specific for its target due to cell engineering using target specific reporter gene constructs

Ordering

Catalog No. Pack Size Price Quantity
51100-7

2.5 ml/vial

 $995.00

Specifications

Formulation Lyophilized in PBS
Molecular Weight 22 kDa, monomer, non-glycosylated
Source Human Cell Expressed (HCE) in HEK-293 cells in the absence of animal-derived products
EC50 Typically 0.4 to 2 ng/ml
Purity 95% (SDS-PAGE stained with Coomassie blue)
Endotoxin level < 1 EU/μg
Storage Lyophilized products are stable for one year at -20°C to -80°C from date of receipt. Upon reconstitution, the cytokine can be stored at 4°C for short term only (< 1 week), or at -20°C to -80°C in aliquots for long term. Avoid repeated freeze-thaw cycles. Refreezing should be performed on dry ice or in a dry ice/alcohol bath.

Tech Info / Data

  1. 11619 Purity Confirmation on SDS-PAGE
Background:

Recombinant Human Growth Hormone (HGH), expressed in engineered human cells, is a member of the somatotropin/prolactin family of hormones. HGH is produced from the pituitary gland and is required for normal human growth and development. HGH modifies a variety of physiological functions by stimulating the expression of insulin-like growth factor I and increases calcium retention and bone mineralization. HGH increases muscle mass, promotes lipolysis and reduces liver uptake of glucose.

Citations

References:

  1. Gout, P. W., et al (1980) Cancer Research 40, 2433-2436.

  2. Goffin, V., et al (1996) Endocrine Reviews 17, 385-410.

Documentation

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