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Anti-Human IFN-Gamma Receptor Chain 2, Clone MMHGR-2 (MAb)

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Anti-Human IFN-Gamma Receptor Chain 2, Clone MMHGR-2 (MAb)

Catalog Number: 21585

This Mouse monoclonal antibody against Human Interferon Gamma Receptor Chain 2 (Clone MMHGR-2) is suitable for use in Direct Binding ELISA

$390.00

Pack Size
Product Info

SpecificityBinds to but does not neutralize human IFN-Gamma receptor
Tested Application
  • Direct Binding ELISA

 

Full Product Name: Anti-Human Interferon Gamma Receptor Chain 2, Clone MMHGR-2 (MAb)

Specifications

FormulationSupplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA)
AntigenHuman interferon gamma receptor chain 
IsotypeIgG1
Host SpeciesMouse
Purity> 95% by SDS-PAGE stained by Coomassie Blue
Endotoxin level < 1 EU/μg
BioactivityMeasured by neutralization of interferon in cytopathic effect inhibition assay.
StorageFor retention of full activity store at -70°C or below and avoid repeated freeze/thaw cycles
Antigen SynonymsNone
CloneMMHGR-2

Citations

4 Citations

 

  1. Conti, Laura, et al. (2007). In the absence of IGF-1 signaling, IFN-gamma suppresses human malignant T-cell growth. Blood Journal, 10 pgs. PMID: 17148586. (link)
  2. Bernabei, Paola, et al. (2003). IGF-1 down-regulates IFN-gamma R2 chain surface expression and desensitizes IFN-gamma/STAT-1 signaling in human T lymphocytes. Blood Journal, 7 pgs. PMID: 12842994. (link)
  3. Rigamonti, Laura, et al. (2000). Surface expression of the IFN-gamma R2 chain is regulated by intracellular trafficking in human T lymphocytes. Journal of Immunology, 8 pgs. PMID: 10605012. (link)
  4. Pestka, Sidney, et al. (1997). The interferon gamma (IFN-gamma) receptor: a paradigm for the multichain cytokine receptor. Cytokine & Growth Factor Reviews, 18 pgs. PMID: 9462485. (link)

 

References

 

  1. Rubinstein, S., Familletti, P.C., and Pestka, S. (1981) "Convenient Assay for Interferons," J. Virol. 37, 755-758
  2. Familletti, P.C., Rubinstein, S., and Pestka, S. (1981) "A Convenient and Rapid Cytopathic Effect Inhibition Assay for Interferon," in Methods in Enzymology, Vol. 78 (S. Pestka, ed.), Academic Press, New York, 387-394
  3. Pestka, S. (1986) "Interferon Standards and General Abbreviations," in Methods in Enzymology (S. Pestka, ed.), Academic Press, New York 119, 14-23

Documentation

Certificate of Analysis (CoA) and Safety Data Sheet (SDS)
21585-1 CoA

21585-1 Certificate of Analysis

21585 SDS

21585 Safety Data Sheet