Anti-Human IFN-Gamma Receptor Chain 2, Clone MMHGR-2 (MAb)
Catalog Number: 21585
This Mouse monoclonal antibody against Human Interferon Gamma Receptor Chain 2 (Clone MMHGR-2) is suitable for use in Direct Binding ELISA
$390.00
Product Info
Specificity
Binds to but does not neutralize human IFN-Gamma receptor
Tested Application
Full Product Name: Anti-Human Interferon Gamma Receptor Chain 2, Clone MMHGR-2 (MAb)
Specifications
| Formulation | Supplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA) |
|---|---|
| Antigen | Human interferon gamma receptor chain |
| Isotype | IgG1 |
| Host Species | Mouse |
| Purity | > 95% by SDS-PAGE stained by Coomassie Blue Endotoxin level < 1 EU/μg |
| Bioactivity | Measured by neutralization of interferon in cytopathic effect inhibition assay. |
| Storage | For retention of full activity store at -70°C or below and avoid repeated freeze/thaw cycles |
| Antigen Synonyms | None |
| Clone | MMHGR-2 |
Citations
4 Citations
- Conti, Laura, et al. (2007). In the absence of IGF-1 signaling, IFN-gamma suppresses human malignant T-cell growth. Blood Journal, 10 pgs. PMID: 17148586. (link)
- Bernabei, Paola, et al. (2003). IGF-1 down-regulates IFN-gamma R2 chain surface expression and desensitizes IFN-gamma/STAT-1 signaling in human T lymphocytes. Blood Journal, 7 pgs. PMID: 12842994. (link)
- Rigamonti, Laura, et al. (2000). Surface expression of the IFN-gamma R2 chain is regulated by intracellular trafficking in human T lymphocytes. Journal of Immunology, 8 pgs. PMID: 10605012. (link)
- Pestka, Sidney, et al. (1997). The interferon gamma (IFN-gamma) receptor: a paradigm for the multichain cytokine receptor. Cytokine & Growth Factor Reviews, 18 pgs. PMID: 9462485. (link)
References
- Rubinstein, S., Familletti, P.C., and Pestka, S. (1981) "Convenient Assay for Interferons," J. Virol. 37, 755-758
- Familletti, P.C., Rubinstein, S., and Pestka, S. (1981) "A Convenient and Rapid Cytopathic Effect Inhibition Assay for Interferon," in Methods in Enzymology, Vol. 78 (S. Pestka, ed.), Academic Press, New York, 387-394
- Pestka, S. (1986) "Interferon Standards and General Abbreviations," in Methods in Enzymology (S. Pestka, ed.), Academic Press, New York 119, 14-23