Anti-Human IFNGR2, Clone MMHGR-2 (MAb)

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Product Features: 
  • Mouse monoclonal antibody against Human IFN Gamma Receptor Chain 2 (Clone MMHGR-2)
  • Suitable for use in Direct Binding ELISA

Full Product Name: Anti-Human Interferon Gamma Receptor Chain 2, Clone MMHGR-2 (MAb)

Ordering

Catalog No. Pack Size Price Quantity
21585-1

250 μg

 $350.00

Specifications

Formulation Supplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA)
Antigen Human interferon gamma receptor chain 
Isotype IgG1
Host Species Mouse
Purity > 95% by SDS-PAGE stained by Coomassie Blue
Endotoxin level < 1 EU/μg
Bioactivity Measured by neutralization of interferon in cytopathic effect inhibition assay.
Specificity Binds to but does not neutralize human IFN-gamma receptor
Storage For retention of full activity store at -70°C or below and avoid repeated freeze/thaw cycles
Antigen Synonyms None
Clone MMHGR-2  

Tech Info / Data

Tested Application:

  • Direct Binding ELISA

Citations

4 Citations:

  1. Conti, Laura, et al. (2007). In the absence of IGF-1 signaling, IFN-gamma suppresses human malignant T-cell growth. Blood Journal, 10 pgs. PMID: 17148586. (link)

  2. Bernabei, Paola, et al. (2003). IGF-1 down-regulates IFN-gamma R2 chain surface expression and desensitizes IFN-gamma/STAT-1 signaling in human T lymphocytes. Blood Journal, 7 pgs. PMID: 12842994. (link)

  3. Rigamonti, Laura, et al. (2000). Surface expression of the IFN-gamma R2 chain is regulated by intracellular trafficking in human T lymphocytes. Journal of Immunology, 8 pgs. PMID: 10605012. (link)

  4. Pestka, Sidney, et al. (1997). The interferon gamma (IFN-gamma) receptor: a paradigm for the multichain cytokine receptor. Cytokine & Growth Factor Reviews, 18 pgs. PMID: 9462485. (link)

    References:

    1. Rubinstein, S., Familletti, P.C., and Pestka, S. (1981) "Convenient Assay for Interferons," J. Virol. 37, 755-758

    2. Familletti, P.C., Rubinstein, S., and Pestka, S. (1981) "A Convenient and Rapid Cytopathic Effect Inhibition Assay for Interferon," in Methods in Enzymology, Vol. 78 (S. Pestka, ed.), Academic Press, New York, 387-394

    3. Pestka, S. (1986) "Interferon Standards and General Abbreviations," in Methods in Enzymology (S. Pestka, ed.), Academic Press, New York 119, 14-23

    Documentation

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