Anti-Mouse IFN Alpha Antibody, Clone RMMA-1, neutralizing (MAb)

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Product Features: 
  • Rat monoclonal antibody against Mouse IFN Alpha
  • Suitable for use in Neutralization and ELISA application
  • Unconjugated

Ordering

Catalog No. Pack Size Price Quantity
22100-1

250 μg

 $495.00

Specifications

Formulation Supplied frozen in 0.3M Sodium Bicarbonate, 0.2M Sodium Chloride
Antigen Mouse interferon alpha
Isotype IgG1
Host Species Rat
Purity > 95% by SDS-PAGE stained by Coomassie Blue
Endotoxin level < 1 EU/μg
Bioactivity Measured by neutralization of interferon in cytopathic effect inhibition assay.
Specificity Neutralizes mouse IFN-alpha; binds to mouse IFN-alpha
Storage For retention of full activity store at -70oC or below and avoid repeated freeze/thaw cycles
Antigen Synonyms Mouse IFN Alpha Rat MAb, Mouse IFN Rat Monoclonal Antibody, Interferon Alpha, IFN Alpha, IFN-a, Type I IFN Alpha
Clone  RMMA-1

Tech Info / Data

Tested Applications:

  • Neutralization
  • ELISA

Suggested Applications*:

  • Immunoprecipitation

*Please note that these applications are presented for suggested use only and have not been fully evaluated by PBL

Citations

Citations:

  1. Neutrophils Recruited by IL-22 in Peripheral Tissues Function as TRAIL-Dependent Antiviral Effectors against MCMV. Stacey et al., 2012, Cell Host Microbe, 15(4):471 (link)

  2. IFN-α-producing PDCA-1+ Siglec-H- B cells mediate innate immune defense by activating NK cells. Bao et al., 2011, Eur. J. Immunol., 41:657 (link)

  3. Efficient co-expression of bicistronic proteins in mesenchymal stem cells by development and optimization of a multifunctional plasmid. Krause et al., 2011, Stem Cell Research & Therapy, 2:15 (link)

References:

  1. Type I interferon dependence of plasmacytoid dendritic cell activation and migration. Asselin-Paturel et al. 2005, J. Exp. Med. 201:1157.

  2. CpG oligonucleotides induce splenic CD19+ dendritic cells to acquire potent indoleamine 2,3-dioxygenasedependent T cell regulatory functions via IFN Type 1 signaling. Mellor et al. 2005, J. Immunol. 175:5601.

Documentation

Rat MAb to Mouse IFN Alpha Titration in L929

Titration of Rat MAb to Mouse Interferon Alpha in the L929 Cell Line

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22100-3 FITC Conjugated Anti-Mouse Interferon Alpha, Clone RMMA-1 (MAb)

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