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Anti-Human IFN-Beta, Rabbit Serum (PAb)

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Anti-Human IFN-Beta, Rabbit Serum (PAb)

Catalog Number: 31410

Unconjugated Rabbit polyclonal antibody against Human IFN-Beta suitable for use in neutralization, ELISA, Western Blot, immunoprecipitation, and immunohistochemistry

$315.00

Pack Size
Product Info

SpecificityBinds to and neutralizes human IFN-Beta
Tested Application
  • Neutralization
Suggested Applications*
  • ELISA
  • Western Blot
  • Immunoprecipitation
  • Immunohistochemistry

 

 

*Please note that these applications are presented for suggested use only and have not been fully evaluated by PBL

 

This antibody is immunized by E.coli expressed human IFN-Beta

Specifications

FormulationSupplied frozen
AntigenRecombinant human interferon beta (expressed in E.coli )
Host SpeciesRabbit
BioactivityMeasured by neutralization of interferon in cytopathic effect inhibition assay using A549 cells challenged with EMCV.
StorageFor retention of full activity store at -70oC or below and avoid repeated freeze/thaw cycles.
Antigen SynonymsHuman Beta Interferon Polyclonal, Human IFNB, Human Fibroblast IFN, Human IFN Beta Rabbit Polyclonal, Human Fibroblast Interferon, Human Beta IFN, Human Type I Interferon Beta, Human IFN B

Citations

4 Citations

 

  1. Kate, W.D. et al., (2024), "Loss of hte DNA repair protein, polynucleotide kinase/phosphatase, activates the type 1 interferon response independent of ionizing radiation", Nucleic Acids Res., PMID: 39087523, DOI: 10.1093/nar/gkae654 (link)
  2. Patel, Mickey, et al. (2012). Uterine Epithelial Cells Specifically Induce Interferon-Stimulated Genes in Response to Polyinosinic-Polycytidylic Acid Independently of Estradiol. PLOS One, 11 pgs. PMID: 22558189. (link)
  3. Dobson-Belaire, Wendy, et al. (2010). Neisseria gonorrhoeae effectively blocks HIV-1 replication by eliciting a potent TLR9-dependent interferon-α response from plasmacytoid dendritic cells. Cellular Microbiology, 15 pgs. PMID: 20735437. (link)
  4. Lee, Sung-Hoon, et al. (2009). The major outer membrane protein of a periodontopathogen induces IFN-beta and IFN-stimulated genes in monocytes via lipid raft and TANK-binding kinase 1/IFN regulatory factor-3. Journal of Immunology, 14 pgs. PMID: 19380831. (link)

 

References

 

  1. Rubinstein, S., Familletti, P.C., and Pestka, S. (1981) J. Virol. 37:75
  2. Budd et al. (1985) Canc. Chem. Pharm. 12:39
  3. Hanibuchi et al. Blood (2006). 107:3716
  4. Kvale et al. Blood (2006) 107:2022
  5. Lande et al. J. Immunol. (2003) 170:1174
  6. Severa et al. J. Leuk. Biol (2006) 79:1286

Documentation

Certificate of Analysis (CoA) and Safety Data Sheet (SDS)
31410-1 CoA

31410-1 Certificate of Analysis

31410 SDS

31410 Safety Data Sheet