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Anti-Human IFN-Beta, Sheep Serum (PAb)

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Anti-Human IFN-Beta, Sheep Serum (PAb)

Catalog Number: 31401

Unconjugated Sheep polyclonal antibody against Human IFN-Beta suitable for use in neutralization, ELISA, Western Blot, immunoprecipitation, and immunohistochemistry

$345.00

Pack Size
Product Info

Specificity Binds to and neutralizes human IFN-Beta
Tested Application
  • Neutralization
Suggested Applications*
  • ELISA
  • Western Blot
  • Immunoprecipitation
  • Immunohistochemistry

 

*Please note that these applications are presented for suggested use only and have not been fully evaluated by PBL

 

This antibody is Immunized by mammalian expressed human IFN-Beta

Specifications

Formulation Supplied frozen in Phosphate buffered saline (PBS)
Antigen Recombinant human interferon beta 1a, mammalian
Host Species Sheep
Bioactivity Measured by neutralization of interferon in cytopathic effect inhibition assay.
Storage For retention of full activity store at -20oC or below and avoid repeated freeze/thaw cycles.
Antigen Synonyms Human Beta Interferon Polyclonal, Human IFNB, Human Fibroblast IFN, Human IFN Beta Sheep Polyclonal, Human Fibroblast Interferon, Human Beta IFN, Human Type I Interferon Beta, Human IFN B

Citations

6 Citations

 

  1. Malle, L. et al., (2023), "Autoimmunity in Down's syndrome via cytokines, CD4T cells and CD11c+B cells", Nature, PMID: 36813963, DOI: 10.1038/s41586-023-05736-y (link)

  2. Ka, N-L., et al., (2022), "Type I IFN Stimulates IFI16-mediated aromatase expression in adipocytes that promotes E2-dependent growth of ER-positive breast cancer", Cell. Mol. Life Sci., 79(6):306, PMID: 35593921, DOI: 10.1007/s00018-022-04333-y (link)

  3. James, Kevin (2016). Deciphering the mechanism(s) which limit reovirus spread in resistant lung and HNSCC cancer cells. University of Alberta, 125 pgs. PMID: no PMID. (link)

  4. Cardenas, Washington, et al. (2006). Ebola Virus VP35 Protein Binds Double-Stranded RNA and Inhibits Alpha/Beta Interferon Production Induced by RIG-I Signaling. JVI, 11 pgs. PMID: 16698997. (link)

  5. Piccioli, Diego, et al. (2002). Contact-dependent Stimulation and Inhibition of Dendritic Cells by Natural Killer Cells. JEM, 7 pgs. PMID: 11828008. (link)

  6. Jacobs, Aaron, et al. (2001). Lipopolysaccharide-induced expression of interferon-beta mediates the timing of inducible nitric-oxide synthase induction in RAW 264.7 macrophages. JBC, 9 pgs. PMID: 11602590. (link)

 

References

 

  1. Rubinstein, S., Familletti, P.C., and Pestka, S. (1981) "Convenient Assay for Interferons," J. Virol. 37, 755-758

  2. Familletti, P.C., Rubinstein, S., and Pestka, S. (1981) "A Convenient and Rapid Cytopathic Effect Inhibition Assay for Interferon," in Methods in Enzymology, Vol. 78 (S. Pestka, ed.), Academic Press, New York, 387-394

  3. Pestka, S. (1986) "Interferon Standards and General Abbreviations," in Methods in Enzymology (S. Pestka, ed.), Academic Press, New York 119, 14-23

Documentation

Certificate of Analysis (CoA) and Safety Data Sheet (SDS)
31401-1 CoA

31401-1 Certificate of Analysis

31401 SDS

31401 Safety Data Sheet