Anti-Human IFN Beta Antibody, Clone MMHB-3 (MAb)

Home / Products / Antibodies / Monoclonal Antibodies (MAbs) / Anti-Human IFN MAbs / Anti-Human IFN Beta Antibody, Clone MMHB-3 (MAb)
Product Features: 
  • Mouse monoclonal antibody against Human IFN Beta (Clone MMHB-3)
  • Suitable for use in Direct Binding ELISA 
  • Suggested applications include Western Blot, flow cytometry, immunoprecipitation and immunohistochemistry
  • Unconjugated

Ordering

Catalog No. Pack Size Price Quantity
21400-1

50 μg

 $215.00

Specifications

Formulation Supplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA)
Antigen Human interferon beta
Isotype IgG1 kappa
Host Species Mouse
Purity > 95% by SDS-PAGE stained by Coomassie Blue
Endotoxin level < 1 EU/μg
Bioactivity Measured by neutralization of interferon in cytopathic effect inhibition assay.
Specificity Binds to human IFN-beta with high affinity
Storage For retention of full activity store at -20°C or below and avoid repeated freeze/thaw cycles
Antigen Synonyms Human Beta Interferon, Human IFNB, Human Fibroblast IFN, Human IFN Beta, Human Fibroblast Interferon, Human Beta IFN, Human Type I Interferon Beta, Human IFN B
Clone MMHB-3

Tech Info / Data

Tested Application:

  • Direct Binding ELISA

Suggested Applications*:

  • Western Blot
  • Flow Cytometry
  • Immunoprecipitation
  • Immunohistochemistry

*Please note that these applications are presented for suggested use only and have not been fully evaluated by PBL

Citations

6 Citations:

  1. Teles, Rosane, et al. (2015). IL-27 suppresses antimicrobial activity in human leprosy. JID, 15 pgs. PMID: 26030183. (link)
  2. Woo, et al. (2013). Developmental Differences in IFN Signaling Affect GATA1s-Induced Megakaryocyte Hyperproliferation. JCI, 14 pgs. PMID: 23863621. (link)
  3. Tamassia, Nicola, et al. (2008). Activation of an immunoregulatory and antiviral gene expression program in poly(I:C)-transfected human neutrophils. Journal of Immunology, 12 pgs. PMID: 18941247. (link)
  4. Moll, Herwig, et al. (2008). Neutralizing Type I Interferon Antibodies trigger an Interferon-Like Response in Endothelial Cells1. Journal of Immunology, 16 pgs. PMID: 18390705. (link)
  5. Reimer, Thornik, et al. (2008). poly(I:C) and LPS induce distinct IRF3 and NF-kappaB signaling during type-I IFN and TNF responses in human macrophages. JLB. PMID: 18252870. (link)
  6. Reimer, Thornik, et al. (2007). Type I IFN induction in response to Listeria monocytogenes in human macrophages: evidence for a differential activation of IFN regulatory factor 3 (IRF3). Journal of Immunology, 13 pgs. PMID: 17617610. (link)

Documentation

Representative Binding Curve

21400-1 Binding Curve

Representative binding curve of antibody to mammalian expressed human interferon beta 1a (circle) and to 1% BSA/PBS (square) in a Direct Binding ELISA. High-binding polystyrene plates were coated with either 1 µg/ml human interferon beta 1a or 1% BSA/PBS. Thereafter, titrations of the product were added to the wells. Donkey and anti-mouse IgG conjugated to HRP was used as the detection antibody. Colorimetric detection was performed using 3,3',5,5'-Tetramethylbenzidine (TMB) substrate. The HRP-TMB reaction was stopped using a diluted H2SO4/HCl solution.

Related Products

Catalog No. Description Pack Size Price Quantity
31401-1 Anti-Human Interferon Beta, Sheep Serum (PAb)

2 x 104 units

 $315.00
21405-1 Anti-Human Interferon Beta, Clone MMHB-1 (MAb)

50 μg

 $200.00

Looking for a CoA?

Find your lot-specific Certificate of Analysis here!

Which service best suits your needs?

Finding the right biomarker detection service to meet your project needs just got easier...

Want to stay in touch?

Sign up for our email list to be kept up-to-date on the latest product releases and company news!

Go to top