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Catalog No. | Pack Size | Price | Quantity |
---|---|---|---|
12125-1 |
1 x 105 units |
$335.00 |
Formulation | Supplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA) |
Molecular Weight | 19.1 kDa |
Source | cDNA obtained from mouse leukocyte interferon expressed in E.coli |
Purity | > 95% by SDS-PAGE stained by Coomassie Blue Endotoxin level < 1 EU/μg |
Bioactivity | Measured using a cytopathic inhibition assay on Mouse (L929) cells with EMCV. The EC50 for IFN in this assay is ~ 5 U/ml. |
Storage | For retention of full activity store at -70°C or below and avoid repeated freeze/thaw cycles |
Synonyms | Mu IFN-α11, Mouse IFN Alpha Subtype, Mouse IFN Protein Subtype, Interferon Alpha, IFN Alpha, IFN-a, Type I IFN Alpha |
Accession Number | AY225954 |
Mouse IFN Alpha 11 was originally identified as an interferon whose expression was not upregulated by viral infection of cells [Coulombel et al. (1991) Gene 104(2):187]
Expression of Mouse IFN Alpha 11 is induced by poly(I):poly(C) and some virus, but not others in L929 cells [Fung et al. (2004) J. Imm. Meth. 284:177]. It has been suggested that expression of this IFN may be regulated by OCT-1 and Ptx-1 [Mesplede et al. (2005) Mol. Cell Biol. 25(19):8717, Lopez et al. Mol. Cell Biol. 10(20):7527]. Additionally, a number of studies have suggested that the expression of this IFN is tightly regulated [reviewed by Doly et al. (1998) Cell. Mol. Life Sci. 54:1109].
Summary: Mouse IFN Alpha 11 is a high activity interferon whose expression has been extensively studied and is tightly regulated.
For more information on Mouse IFN Alpha subtype nomenclature click here.
2 Citations:
References:
The activity of Mouse IFN Alpha 11 and Mouse IFN Alpha A was compared. The EC50 for Mouse IFN Alpha 11 was 7 pg/ml.
Results are representative and may vary depending upon experimental conditions.
Catalog No. | Description | Pack Size | Price | Quantity |
---|---|---|---|---|
12100-1 |
Mouse Interferon Alpha A |
1 x 105 units |
$425.00 |
|
12115-1 |
Mouse Interferon Alpha 4, mammalian |
1 x 105 units |
$385.00 |
|
22100-1 |
Anti-Mouse Interferon Alpha, Clone RMMA-1 (MAb) |
250 μg |
$515.00 |
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Quick Search
PBL’s improved site search function is defaulted to an exact match.
Search Term Results |
|
IFN beta |
All interferon beta products and related technical information (e.g. technical notes) |
Human IFN beta |
All human interferon products related technical information (e.g. technical notes) |
IL-2 |
All products contain the term “IL-2”, including IL-23 |
IL 2 |
All products contain the term “IL 2”, including IL-23 |
Erythropoietin |
All EPO products and technical information |
Eryth |
All EPO products and technical information |
The results are displayed in best match products grouped in the following product category filters:
Each filter contains sub-categories for further narrowing of your search results
Other web content such as technical notes that contain the Search Term can be displayed by checking the box next to the corresponding filter on the left side of the Search Results Page.