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Catalog No. | Pack Size | Price | Quantity |
---|---|---|---|
12400-1 |
1 x 105 units |
$495.00 |
Formulation | Supplied frozen in 20mM HEPES, pH 6.0; 0.5M NaCl; 6% glycerol; 0.1% Bovine Serum Albumin (BSA) |
Molecular Weight | 19.6 kDa |
Source | Gene was obtained from mouse DNA expressed in E. coli modified as described in Day, et al. (1992) "Engineered disulfide bond greatly increases specific activity of recombinant murine interferon beta" (J. Interferon Res. 12: 139-43). |
Purity | > 95% by SDS-PAGE stained by Coomassie Blue Endotoxin level < 1 EU/μg |
Bioactivity | Measured using a cytopathic effect inhibition assay on Mouse (L929) cells with EMCV. EC50 for IFNβ is ~ 2.5U/ml |
Storage | For retention of full activity store at -70°C or below and avoid repeated freeze/thaw cycles |
Synonyms | Mouse Beta IFN, Mouse Beta Interferon, Mouse IFN Beta, Mouse IFNB, Mouse Type I IFN beta, Mouse Fibroblast IFN, Mouse Fibroblast Interferon, Mouse Type I Interferon Beta |
Interferon Beta (IFN Beta) is generally the first Type I IFN to be expressed after viral infection. In the mouse both IFN Beta and IFN Alpha 4 prime cells for the production of the other Type I IFNs. Mouse IFN Beta was originally cloned by Higashi et al. [(1983) J. Biol. Chem. 258(15):9522] and has been engineered to contain a disulfide which confers added stability.
52 Citations:
References: (For additional references, please refer to the Certificate of Analysis)
The activity of Mouse IFN Beta with carrier (PBL 12400) and Mouse IFN beta, carrier-free (PBL 12401) was compared in the L929/EMCV CPE assay. The EC50 for Mouse IFN Beta in this experiment was 1.8 U/ml while the EC50 for Mouse IFN Beta (CF) was 1.5 U/ml when calibrated to the international standard.
Results are representative and may vary depending upon experimental conditions.
Catalog No. | Description | Pack Size | Price | Quantity |
---|---|---|---|---|
12405-1 |
Mouse Interferon Beta, mammalian |
1 x 105 units |
$270.00 |
|
32400-1 |
Anti-Mouse Interferon Beta, Rabbit Serum (PAb) |
2 x 104 units |
$365.00 |
|
22400-1 |
Anti-Mouse Interferon Beta, Clone RMMB-1 (MAb) |
250 μg |
$375.00 |
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PBL Assay Science offers scientists a comprehensive range of assay kits, interferons, cytokines, growth factors and antibodies. Our high quality products provide consistent, reliable performance and are suitable for use in a range of research applications.
Quick Search
PBL’s improved site search function is defaulted to an exact match.
Search Term Results |
|
IFN beta |
All interferon beta products and related technical information (e.g. technical notes) |
Human IFN beta |
All human interferon products related technical information (e.g. technical notes) |
IL-2 |
All products contain the term “IL-2”, including IL-23 |
IL 2 |
All products contain the term “IL 2”, including IL-23 |
Erythropoietin |
All EPO products and technical information |
Eryth |
All EPO products and technical information |
The results are displayed in best match products grouped in the following product category filters:
Each filter contains sub-categories for further narrowing of your search results
Other web content such as technical notes that contain the Search Term can be displayed by checking the box next to the corresponding filter on the left side of the Search Results Page.