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Proteins

Antibodies

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Proteins

Recombinant Human IFN-α 2a (Catalog No. 11100-1) Sialoadhesin Expressed on IFN-Induced Monocytes Binds HIV-1 and Enhances Infectivity, Rempel et al. (2008), PloS, 3(4):e1967
Universal Type I [IFN-αA/D (Bgl ll)] (Catalog No. 11200-1) Parainfluenza virus 5 genome are located in viral cytoplasmic bodies whilst the virus dismantles the interferon-induced antiviral state of cells, Carlos et al., (2009), J. Gen. Virol., 90:2147
  Abortive versus Productive Viral Infection of Dendritic Cells with a Paramyxovirus Results in Differential Upregulating of Select Costimulatory Molecules, Alexander-Miller et al., (2005), J. Virol.,  79(12):7544
Recombinant Human IFN-β (Catalog No. 11410) A Five-Amino-Acid Deletion of the Eastern Equine Encephalitis Virus Capsid Protein Attenuates Replication in Mammalian Systems but Not in Mosquito Cells, Aguilar et al., (2008), J. Virol., 82(14):6972
  Ebola Virus VP24 Proteins Inhibit the Interaction of NPI-1 Subfamily Karyopherin α Proteins with Activated STAT1, Reid et al.,  (2007), J. Virol., 81(24):13469
Recombinant Mouse IFN-αA (Catalog No. 12100-1) Type I IFN Negatively Regulates CD8+ T Cell Responses through IL-10-Producing CD4+ T Regulatory 1 Cells, Dikopoulos et al., (2005), J. Immunol., 174:99
Recombinant Mouse IFN-α4 (Catalog No. 12115-1) Lipopolysaccharide-Mediated Il-10 Transcriptional Regulation Requires Sequential Induction of Type I IFNs and Il-27 in Macrophages, Iyer et al. (2012), J. Immunol., 185:6599
Recombinant Mouse IFN-α11 (Catalog No. 12125-1) Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response, Swanson et al., (2010), JEM, 207:1485
Recombinant Mouse IFN-β (Catalog No. 12400-1) Gene-Based Intramuscular Interferon-β Therapy for Experimental Autoimmune Encephalomyelitis, Jaini et al., (2006), Mol. Therapy., 14(3):416
  Mouse Hepatitis Virus Does Not Induce Beta Interferon Synthesis and Does Not Inhibit Its Induction by Double-Stranded RNA, Zhou and Perlman, (2007), J. Virol., 81(2):568
Selected citations only. For a more comprehensive list, please contact techservice@pblassaysci.com.

 

 

Antibodies

Anti-Human Interferon Alpha, Monoclonal (Catalog No. 21100-1) Receptor Cross-Linking on Human Plasmacytoid Dendritic Cells Leads to the Regulation of IFN-(alpha) Production, Fanning et al., (2006), J. Immunol., 177:5829
  Characterization of Virus-Responsive Plasmacytoid Dendritic Cells in the Rhesus Macaque, Chung et al.., (2005), Clin. Diagn. Lab. Immunol., 12(3):426
Anti-Human Interferon Alpha, Monoclonal (Catalog No. 21105-1) Contact-dependent Stimulation and Inhibition of Dendritic Cells by Natural Killer Cells, Piccioli et al., (2002), J. Exp. Med., 195(3):335
Anti-Human Interferon Alpha/Beta Receptor Chain 2, Monoclonal (Catalog No. 21385-1) Comparable potency of IFNα2 and IFNβ on immediate JAK/STAT activation but differential down-regulation of IFNAR2, Marijanovic et al., (2007), Biochem. J., 407:141
  Plasmacytoid predendritic cells initiate psoriasis through interferon-α production, Nestle et al., (2005), J. Exp. Med., 202(1):135
  Virus overrides the propensity of human CD40L-activated plasmacytoid dendritic cells to produce Th2 mediators through synergistic induction of IFN-γ and Th1 chemokine production, Bendriss-Vermare et al., (2005), J. Leu. Biol., 78:954
Anti-Mouse Interferon Alpha and Anti-Mouse Interferon Beta, Monoclonal (Catalog Nos. 22100-1 and 22400-1) Induction of type I IFN is required for overcoming tumor-specific T-cell tolerance after stem cell transplantation, Horkheimer et al., (2009), Blood, 113(21):5330
FITC Conjugated Anti-Mouse Interferon Alpha, Monoclonal (Catalog No. 22100-3) TLR9 Blockade Inhibits Activation of Diabetogenic CD8+ T Cells and Delays Autoimmune Diabetes, Zhang et al., (2010), J. Immunol., 184:5645
Anti-Human Interferon Beta, Polyclonal (Catalog  No. 31400-1) Ebola Virus VP53 Protein Binds Double-Stranded RNA and Inhibits Alpha/Beta Interferon Production Induced by RIG-1 Signaling, Basler et al., (2006), J. Virol., 80(11):5168 
Selected citations only. For a more comprehensive list, please contact techservice@pblassaysci.com.

 

 

Assay Kits

High Sensitivity Human Interferon Beta ELISA (Catalog No. 41415-1) Phagosomal signaling by Borrelia burgdorferi  in human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-β, Cervantes et al.,  (2011), PNAS,  108(9):3683
  Human Papillomavirus Type 16 E5 Protein Induces Expression of Beta Interferon through Interferon Regulatory Factor 1 in Human Keratinocytes, Muto et al.,  (2011),  J. Virol., 85(10):5070
  Interferon regulator factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway, Tarassishin, et al.,  (2011),  J. NeuroInflamm., 8:187
Human Interferon Alpha ELISA (Catalog No. 41100) DIfferential CD4+ T-Lymphocyte Apoptosis and Bystander T-Cell Activation in Rhesus Macaques and Sooty Manabeys during Acute Simian Immunodeficiency Virus Infection, Meythaler et al., (2009),  J. Virol., 83(2):572
Human Interferon Alpha Multi-Subtype ELISA (Catalog No. 41105-1) Role of atopic status in Toll-like receptor (TLR) 7- and TLR9-mediated activation of human eosinophils, Mansson et al.,  (2009),  J. Leu. Biol., 85:719
  Gene Expression of Nucleic Acid-Sensing Pattern Recognition Receptors in Children Hospitalized for Respiratory Syncytial Virus-Associated Acute Bronchitis, Scagnolari et al.,  (2009), Clin. Vacc. Immunol., 16(6):816
Human Interferon Alpha Multi-Subtype Serum ELISA (Catalog No. 41110-1) Pharmacokinetics, tissue distribution, excretion, and antiviral activity of pegylated recombinant human consensus interferon-α variant in monkeys, rats and guinea pigs, Cai et al., (2012), Regulatory Peptides, 173(1-3):74-81
  Impact of low dose naltrexone (LDN) on antiretroviral therapy (ART) treated HIV+ adults in Mali: A single blind randomized clinical trial, Traore et al., (2011), J. AIDS HIV Res., 3:10:189-198
  Decreased numbers of peripheral blood dendritic cells in patients with coronary artery disease are associated with diminished plasma Flt3 ligand levels and impaired plasmacytoid dendritic cell function, Brussel et al., (2011), Clinical Science, 120:415-426
  Interferon β is associated with type 1 interferon-inducible gene expression in dermatomyositis, Liao et al., (2011), Ann Rheum Dis, 70(5):831-836
  Codelivery of PEG-IFN-α inhibits HCV DNA vaccine-induced T cell response but not humoral responses in African green monkeys, Park et al., (2008), Vaccine, 26(32):3978-3983
  Combined analysis of monocyte and lymphocyte messenger RNA expression with serum protein profiles in patients with scleroderma, Duan et al, (2008), Arthritis & Rheumatism, 58(5): 1465-1474
Human Interferon Beta ELISA (Catalog No. 41410) TRIM21 Is essential to Sustain IFN Regulatory Factor 3 Activation during Antiviral Response, Yang et al.,  (2009),  J. Immunol.,  182:3782
  IRF-5 Is a Mediator of the Death Receptor-Induced Apoptotic Signaling Pathway, Hu and Barbes, (2009), J. Biol. Chem., 284(5):2767
Mouse Interferon Alpha ELISA(Catalog No.  42120) Rotavirus Replication in the Cholangiocyte Mediates the Temporal Dependence of Murine Biliary Atresia, Mohanty et al., (2013), PLoS One 8(7): e69069
  The Fusion Protein of IFN-α and Apolipoprotein A-I Crosses the Blood-Brain Barrier by a Saturable Transport Mechanism, Floravanti et al., (2012), The Journal of Immunology, 188(8):3988-3992
  siRNA-induced immunostimulation through TLR7 promotes antitumoral activity against HPV-driven tumors in vivo, Khairuddin et al., (2012), Immunology and Cell Biology, 90: 187-196
  Auto-Antigenic Protein-DNA Complexes Stimulate Plasmacytoid Dendritic Cells to Promote Atherosclerosis Clinical Perspective, Doring et al., (2012), Circulation, 125:1673-1683.
  The Dominant-Negative Inhibition of Double-Stranded RNA-Dependent Protein Kinase PKR Increases the Efficacy of Rift Valley Fever Virus MP-12 Vaccine, Lihoradova et al., (2012), Journal of Virology, 86(14):7650-7661
  Systemic delivery of therapeutic small interfering RNA using a pH-triggered amphiphilic poly-L-lysine nanocarrier to suppress prostate cancer growth in mice, Guo et al., (2012), European Journal of Pharmaceutical Sciences, 45(5):521-532
  Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus, Walsh et al., (2011), PNAS, 108(29):12018-12023
   AAV2-Mediated Subretinal Gene Transfer of hIFN-α Attenuates Experimental Autoimmune Uveoretinitis in Mice, Tian et al., (2011), PLoS One 6(5): e19542
  The Efficacy of Radiotherapy Relies upon Induction of Type I Interferon-Dependent Innate and Adaptive Immunity, Burnette et al., (2011), Cancer Research, 71:2488
  Ebolavirus VP35 suppresses IFN production from conventional but not plasmacytoid dendritic cells, Leung et al., (2011), Immunology and Cell Biology, 89:792-802
  Pathogenesis and Immune Response of Crimean-Congo Hemorrhagic Fever Virus in a STAT-1 Knockout Mouse Model, Bente et al., (2010), Journal of Virology, 84(21):11089-11100
  IFNα kinoid vaccine-induced neutralizing antibodies prevent clinical manifestations in a lupus flare murine model, Zagury et al., (2009), PNAS, 106(13):5294
  Type I IFN-Mediated Protection of Macrophages and Dendritic Cells Secures Control of Murine Coronavirus Infection, Cervantes-Barragan et al.,  (2009),  J. Immunol., 182:1099
Mouse Interferon Beta ELISA (Catalog No. 42400) Vesicular Stomatitis Virus M Protein Mutant Stimulates Maturation of Toll-Like Receptor 7 (TLR7)-Positive Dendritic Cells through TLR-Dependent and Independent Mechanisms, Ahmed et al., (2009), J. Virol., 83(7):2962
  Interferon β induces mature dendritic cell apoptosis through caspase-11/caspase-3 activation, Yen and Ganes, (2009), Blood, 114(7):1344
  Murine Norovirus I Infection Is Associated with Histopathological Changes in Immunocompetent Hosts, but Clinical Disease Is Prevented by STAT1-Dependent Interferon Responses, Mumphrey et al.,  (2007), J. Virol., 81(7):3251
Selected citations only. For a more comprehensive list, please contact techservice@pblassaysci.com.