Powered by BiozThis well-cited and popular Anti-Human IFNAR2 antibody blocks the biological action of Human Type I interferons. It is suitable for use in Type I IFN neutralization, flow cytometry, immunohistochemistry, and immunoprecipitation.
Anti-Human IFN-Alpha/Beta Receptor Chain 2, Clone MMHAR-2 (MAb)
$665.00
Neutralization Effect of PBL Anti-Human IFNAR2 Monoclonal Antibody (21385) on Human IFN-Alpha 2a (11100) and IFN-Beta (11415) Activities in an A549 Cell/EMCV CPE Assay.
Product Info
| Specificity | Neutralizes human IFN-Alpha receptor; interacts with extracellular domain; binds to human IFN-Alpha receptor with high affinity; blocks biological action of Type I IFNs |
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| Tested Application |
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| Suggested Applications* |
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*Please note that these applications are presented for suggested use only and have not been fully evaluated by PBL.
The Type I interferon receptor is a heterodimer consisting of IFNAR1 and IFNAR2. The IFNAR2 subunit provides most of the binding affinity for IFN and IFNAR1 is required for optimum signaling.
Full Product Name: Anti-Human Interferon Alpha/Beta Receptor Chain 2, Clone MMHAR-2 (MAb)
Documentation
Certificate of Analysis (CoA) and Safety Data Sheet (SDS)
21385-1 CoA
21385-1 Certificate of Analysis
21385 SDS
21385 Safety Data Sheet
| Formulation | Supplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA) |
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| Antigen | Human interferon alpha/beta receptor chain 2 (Human IFNAR2) |
| Isotype | IgG2A |
| Host Species | Mouse |
| Purity | > 95% by SDS-PAGE stained by Coomassie Blue Endotoxin level < 1 EU/μg |
| Bioactivity | Measured by neutralization of interferon in cytopathic effect inhibition assay. |
| Storage | For retention of full activity store at -70°C or below and avoid repeated freeze/thaw cycles |
| Antigen Synonyms | None |
| Clone | MMHAR-2 |