Skip to main content

Anti-Mouse IFN-Alpha, Clone RMMA-1 (MAb)

Hero Region

Anti-Mouse IFN-Alpha, Clone RMMA-1 (MAb)

Catalog Number: 22100

This unconjugated Rat monoclonal antibody against Mouse Interferon Alpha is suitable for use in Neutralization and ELISA applications.

$560.00

Pack Size
Product Info

Specificity Neutralizes mouse IFN-Alpha; binds to mouse IFN-Alpha
Tested Applications
  • Neutralization
  • ELISA
Suggested Application*
  • Immunoprecipitation

 

*Please note that these applications are presented for suggested use only and have not been fully evaluated by PBL

Specifications

Formulation Supplied frozen in 0.3M Sodium Bicarbonate, 0.2M Sodium Chloride
Antigen Mouse interferon alpha
Isotype IgG1
Host Species Rat
Purity > 95% by SDS-PAGE stained by Coomassie Blue
Endotoxin level < 1 EU/μg
Bioactivity Measured by neutralization of interferon in cytopathic effect inhibition assay.
Storage For retention of full activity store at -70oC or below and avoid repeated freeze/thaw cycles
Antigen Synonyms Mouse IFN Alpha Rat MAb, Mouse IFN Rat Monoclonal Antibody, Interferon Alpha, IFN Alpha, IFN-a, Type I IFN Alpha
Clone  RMMA-1

Citations

4 Citations

 

  1. Luo, H. et al., (2023), "NCF1-dependent production of ROS protects against lupus by regulating plasmacytoid dendritic cell development and functions", JCI Insight, PMID: 38653827, DOI: 10.1172/jci.insight.164875 (link)

  2. Neutrophils Recruited by IL-22 in Peripheral Tissues Function as TRAIL-Dependent Antiviral Effectors against MCMV. Stacey et al., 2012, Cell Host Microbe, 15(4):471 (link)

  3. IFN-α-producing PDCA-1+ Siglec-H- B cells mediate innate immune defense by activating NK cells. Bao et al., 2011, Eur. J. Immunol., 41:657 (link)

  4. Efficient co-expression of bicistronic proteins in mesenchymal stem cells by development and optimization of a multifunctional plasmid. Krause et al., 2011, Stem Cell Research & Therapy, 2:15 (link)

 

References

 

  1. Type I interferon dependence of plasmacytoid dendritic cell activation and migration. Asselin-Paturel et al. 2005, J. Exp. Med. 201:1157.

  2. CpG oligonucleotides induce splenic CD19+ dendritic cells to acquire potent indoleamine 2,3-dioxygenasedependent T cell regulatory functions via IFN Type 1 signaling. Mellor et al. 2005, J. Immunol. 175:5601.

Documentation

Certificate of Analysis (CoA) and Safety Data Sheet (SDS)
22100-1 CoA

22100-1 Certificate of Analysis

22100-1 SDS

22100-1 Safety Data Sheet