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Human IFN-Alpha D (Alpha 1)

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Human IFN-Alpha D (Alpha 1)

Catalog Number: 11125

Human IFN-Alpha 1 recombinant protein expressed in E.coli

$335.00

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Product Info

Recombinant Human Interferon Alpha D (Hu-IFN-alpha D; Hu-[Val114] IFN-Alpha 1) obtained from human leukocyte mRNA expressed in E.coli.

 

IFN-Alpha 1 is one of the many interferon alpha subtypes belonging to the Type I leukocyte IFN family. The Type I IFN family has antiviral, anti-proliferative, and natural killer cell activities.

 

  • Expression is induced by viral infection
  • Encoding gene IFNA1 at position Val114

Specifications

Formulation Supplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA)
Molecular Weight 19.4 kDa
Source cDNA obtained from human leukocyte mRNA expressed in E.coli
Purity > 95% by SDS-PAGE stained by Coomassie Blue 
Bioactivity Measured using a cytopathic inhibition assay on Bovine Kidney Cells (MDBK) with Vesicular Stomatis Virus (VSV); human lung carcinoma cell line A549 with encephalomyocarditis virus (EMCV)
Storage For retention of full activity store at -70 ºC or below and avoid repeated freeze-thaw cycles
Synonyms Hu-[Val114] IFN-α1 
Accession Number V00538

Citations

3 Citations

 

  1. Wilson, Timothy R, et al. (2012). Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature, 12 pgs. PMID: 22763448. (link)
  2. Wu, TG, et al. (2007). IFN-alpha-induced murine B16 melanoma cancer vaccine cells: induction and accumulation of cell-associated IL-15. Journal of Interferon & Cytokine Research. PMID: 17266439. (link)
  3. Kang, Dong-Chul, et al. (2004). Expression Analysis and Genomic Characterization of Human Melanoma Differentiation Associated Gene-5, mda-5: a Novel Type I Interferon-Responsive Apoptosis-Inducing Gene. Oncogene, 12 pgs. PMID: 14676839. (link)

Documentation

Certificate of Analysis (CoA) and Safety Data Sheet (SDS)
11125-1 CoA

11125-1 Certificate of Analysis (CoA)

11125 SDS

11125 Safety Data Sheet