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Product Name: VeriKine-HS Human Interferon Beta Serum ELISA Kit (LOQ 1.2 pg/ml)
Catalog No. | Pack Size | Price | Quantity |
---|---|---|---|
41415-1 |
1 x 96-well plate |
$725.00 |
Compatibility: Serum, Plasma, Tissue Culture Media
ELISA Assay Range: 1.2 - 150 pg/ml
Speed: Incubation time, 3 hours, 30 minutes
Specificity: Human Interferon Beta 1a, Human Interferon Beta 1b (No cross-reactivity against human IFN-alpha, IFN-gamma, IFN-omega, IL-6; mouse IFN-alpha, IFN-beta; or rat IFN-beta.)
Synonyms: Human Beta Interferon, Human Fibroblast IFN, Human IFN Beta, Human Fibroblast Interferon, Human Beta IFN, Human Type I Interferon Beta, Human IFN B
Inter-Assay CV: < 8%
Intra-Assay CV: < 10%
Spike Recovery: > 90% in Serum
Storage: 2-8°C
Expiration Date: One year from date of manufacture
Shipping Condition: Wet Ice
Materials Provided:
Detailed Related Product Information:
The High Sensitivity Human IFN Beta Serum ELISA Kit has been developed to measure low/basal levels of human IFN-beta in autoimmune sera, normal serum/ plasma or tissue culture media samples by sandwich enzyme linked immunosorbent assay (ELISA). This assay is suitable for measurement of trademarked therapeutic molecules in human serum samples. Researchers and clinical investigators examining a) the pharmacokinetics of IFN-beta molecules, b) IFN-beta as a biomarker, or c) IFN-beta as a pharmacodynamic marker of TLR agent or other immune response modifier activity will find this highly sensitive and specific assay to be an essential laboratory tool.
Interferon beta (IFN-beta) is part of the first wave of cytokine response in cells. Pathogen infection can result in the activation of interferon regulatory factor 3 (IRF3) that functions in trans to activate IFN beta gene transcription. IFN-beta is biologically unique when compared to other interferons and studies have shown that IFN-beta has overlapping and distinct gene expression patterns as compared to IFN-alpha. It appears that IFN-beta binds to the Type I IFN receptor with higher affinity than the other Type I IFNs and it may also regulate receptor internalization in a different manner. Additionally, IFN-beta has long been known to inhibit viral replication as part of the body’s innate antiviral response and is used as a therapeutic for treatment of multiple sclerosis and some tumors.
Posters:
45 Citations:
References: (For additional references, please refer to the protocol booklet.)
IFN Beta is quantifiable in 86% of MS patients on IFN Beta therapy, 4.1% of MS patients on other therapies and 1.5% of Normal Donor samples.
Catalog No. | Description | Pack Size | Price | Quantity |
---|---|---|---|---|
41435-1 |
VeriKine-HS Human IFN Beta TCM ELISA Kit new Compatibility: Tissue Culture Media Assay Range: 2.34 - 150 pg/ml |
1 x 96-well plate |
$485.00 |
|
41410-1 |
VeriKine Human Interferon Beta ELISA Kit Compatibility: Tissue Culture Media Assay Range: 50-4000 pg/ml |
1 x 96-well plate |
$645.00 |
|
41410-2 |
VeriKine Human Interferon Beta ELISA Kit Compatibility: Tissue Culture Media Assay Range: 50-4000 pg/ml |
5 x 96-well plate |
$2,370.00 $2,625.00 |
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PBL Assay Science offers scientists a comprehensive range of assay kits, interferons, cytokines, growth factors and antibodies. Our high quality products provide consistent, reliable performance and are suitable for use in a range of research applications.
Quick Search
PBL’s improved site search function is defaulted to an exact match.
Search Term Results |
|
IFN beta |
All interferon beta products and related technical information (e.g. technical notes) |
Human IFN beta |
All human interferon products related technical information (e.g. technical notes) |
IL-2 |
All products contain the term “IL-2”, including IL-23 |
IL 2 |
All products contain the term “IL 2”, including IL-23 |
Erythropoietin |
All EPO products and technical information |
Eryth |
All EPO products and technical information |
The results are displayed in best match products grouped in the following product category filters:
Each filter contains sub-categories for further narrowing of your search results
Other web content such as technical notes that contain the Search Term can be displayed by checking the box next to the corresponding filter on the left side of the Search Results Page.