Human IFN-Omega inhibits the proliferation of a variety of tumor cell lines in vitro, stimulates natural killer cell activity, and enhances the expression of major histocompatibility complex class I antigens.
Product Info
IFN-Omega is a Type I interferon closely related to the interferon alpha subtypes, sharing approximately 60% sequence identity with IFN-Alpha and signaling through the same IFNAR1/IFNAR2 receptor complex. Like other members of the Type I IFN family, IFN-Omega exhibits antiviral, anti-proliferative, and immunomodulatory activities, including the activation of natural killer cells.
Documentation
Certificate of Analysis (CoA) and Safety Data Sheet (SDS)
11395-1 CoA
11395-1 Certificate of Analysis (CoA)
11395 SDS
11395-1 Safety Data Sheet
| Formulation | Supplied frozen with a carrier protein |
|---|---|
| Molecular Weight | 20 kDa |
| Source | Recombinant Hu-IFN-ω expressed in E.coli |
| Purity | > 95% by SDS-PAGE stained by Coomassie Blue Endotoxin level < 1 EU/μg |
| Bioactivity | Measured using a cytopathic inhibition assay on human lung carcinoma cell line A549 with encephalomyocarditis virus (EMCV) |
| Storage | For retention of full activity store at -70°C or below and avoid repeated freeze/thaw cycles |
| Synonyms | IFN-ω |
| Accession Number | X58822 |