Rat IFN-Alpha 1, Mammalian
Catalog Number: 13101
Recombinant Rat Interferon Alpha 1 (IFNa1) expressed in mammalian cells with activity measured on rat epithelial-like cells (RATEC).
|Bioactivity||Measured on rat epithelial-like cells (RATEC) challenged with VSV in the presence of 2 mM Glutathione. For full activity, it is recommended that the reducing agent glutathione is added to the culture medium. IFN was titrated with the use of the cytopathic effect inhibition assay.
Typical Activity (EC50) is 20-100 pg/ml.
|Formulation||Supplied frozen in phosphate-buffered saline (PBS) containing 0.1% bovine serum albumin (BSA)|
|Molecular Weight||19.0 kDa|
|Source||Rat Alpha 1 gene expressed in mammalian cells|
|Purity||Greater than 95%|
|Storage||For retention of full activity store at -70°C or below and avoid repeated freeze/thaw cycles|
- Danastas, K. et al., (2023), "Interferon inhibits the release of herpes simplex virus-1 from the axons of sensory neurons", mBio, e0181823, PMID: 37655893, DOI: 10.1128/mbio.01818-23 (link)
- Horst, Ellis, et al. (2018). Elevated Monocyte-Specific Type I Interferon Signalling Correlates Positively with Cardiac Healing in Myocardial Infarct Patients but Interferon Alpha Application Deteriorates Myocardial Healing in Rats. Basic Research in Cardiology, 12 pgs. PMID: 30443679. (link)