Human IFN-Gamma
Catalog Number: 11500
Human Interferon Gamma recombinant protein expressed in E.coli.
$215.00
Product Info
- Type II IFN
- Non-glycosylated polypeptide dimer
Specifications
| Formulation | Supplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA) |
|---|---|
| Molecular Weight | 16.8 kDa |
| Source | Human cDNA obtained from human T lymphocyte expressed in E.coli |
| Purity | > 95% by SDS-PAGE stained by Coomassie Blue Endotoxin level < 1 EU/μg |
| Bioactivity | Measured using a cytopathic inhibition assay on human lung carcinoma cell line A549 with encephalomyocarditis virus (EMCV) |
| Storage | For retention of full activity store at -70oC or below and avoid repeated freeze/thaw cycles |
| Synonyms | None |
| Accession Number | V00543 |
Tech Info & Data
Citations
11 Citations
- Shiffer, E.M. et al., (2024), "Parainfluenza Virus 5 V Protein Blocks Interferon Gamma-Mediated Upregulation of NK Cell Inhibitory Ligands and Improves NK Cell Killing of Neuroblastoma Cells", Viruses, 16(8):1270, DOi: 10.3390/v16081270 (link)
- Eisfeld, A.J. et al., (2024), "A compendium of multi-omics data illuminating host responses to lethal human virus infections", Sci Data., 11(1):328, PMID: 38565538, DOI: 10.1038/s41597-024-03124-3 (link)
- Crawford, J.D., et al., (2023), "The XIST lncRNA is a sex-specific reservoir of TLR7 ligands in SLE", JCI Insight., e169344, PMID: 37733447, DOI: 10.1172/jci.insight.169344 (link)
- Fung, S. K., et al.,(2022), "SARS-CoV-2 NSP13 helicase suppresses interferon signaling by perturbing JAK1 phosphorylation of STAT1", Cell & Bioscience, 12:36, DOI: 10.1186/s13578-022-00770-1, PMID: 35317858, (link)
- Abt, E.R., et al., (2022), "Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells", Cell Reports, 38:110236, DOI: 10.1016/j.celrep.2021.110236 (link)
- Le-Trilling, Vu Thuy Khanh, et al. (2020). The Human Cytomegalovirus pUL145 Isoforms Act as Viral DDB1-Cullin-Associated Factors to Instruct Host Protein Degradation to Impede Innate Immunity. Cell Reports, 19 pgs. PMID: 32075763. (link)
- Raviram, Ramya, et al. (2018). Analysis of 3D genomic interactions identifies candidate host genes that transposable elements potentially regulate. Genome Biology, 19 pgs. PMID: 30541598. (link)
- Kativhu, Chido, et al. (2016). A Model to Explain How the Bacille Calmette Guerin (BCG) Vaccine Drives Interleukin-12 Production in Neonates. PLOS One, 12 pgs. PMID: 27571272. (link)
- Neufeldt, Christopher, et al. (2013). Hepatitis C Virus-Induced Cytoplasmic Organelles Use the Nuclear Transport Machinery to Establish an Environment Conducive to Virus Replication. PLOS Pathogens, 15 pgs. PMID: 24204278. (link)
- Trilling, Mirko, et al. (2009). Gamma Interferon-Induced Interferon Regulatory Factor 1-Dependent Antiviral Response Inhibits Vaccinia Virus Replication in Mouse but Not Human Fibroblasts. JVI, 36 pgs. PMID: 19211768. (link)
- Desloges, Nathalie, et al. (2005). Role of the protein kinase PKR in the inhibition of varicella-zoster virus replication by beta interferon and gamma interferon. Journal of General Virology, 6 pgs. PMID: 15604425. (link)