Anti-Human IFN Alpha Antibody, Clone MMHA-11, neutralizing (MAb)

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Product Features: 
  • Mouse monoclonal antibody against Human IFN Alpha (Clone MMHA-11)
  • Suitable for use in neutralization and ELISAs
  • Unconjugated

Ordering

Catalog No. Pack Size Price Quantity
21112-1

50 μg

 $315.00

Specifications

Formulation Supplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA)
Antigen Human leukocyte interferon
Isotype IgG1 kappa
Host Species Mouse
Purity > 95% by SDS-PAGE stained by Coomassie Blue
Endotoxin level < 1 EU/μg
Bioactivity Measured by neutralization of interferon in cytopathic effect inhibition assay.
Specificity Neutralizes human IFN-alpha; binds to human IFN-alpha
Storage For retention of full activity store at -70°C or below and avoid repeated freeze/thaw cycles
Antigen Synonyms IFN alpha MAb, IFN-a, interferon alpha monoclonal, IFN alpha 2, IFN-a2, interferon alpha 2, Leukocyte interferon, Leukocyte IFN, alpha interferon, interferon alfa, IFN alfa, interferon alpha 2a, IFN alpha 2a, interferon a, interferon alpha 2b, IFN alpha 2b, Type I interferon alpha, Type I IFN alpha
Clone MMHA-11

Tech Info / Data

Tips, Tools and Troubleshooting:

  • Antibodies against Human IFN-α Subtype Specificities Comparison Chart (link)

Tested Applications:

  • Neutralization
  • ELISA

Citations

6 Citations:

  1. Gujer, et al. (2011). Human and Rhesus Plasmacytoid Dendritic Cell and B-Cell Responses to Toll-Like Receptor Stimulation. Immunology, 13 pgs. PMID: 21977996. (link)

  2. Richez, C, et al. (2009). TLR4 ligands induce IFN-alpha production by mouse conventional dendritic cells and human monocytes after IFN-beta priming. Journal of Immunology. PMID: 19124725. (link)

  3. Gantier, Michael, et al. (2008). TLR7 is involved in sequence-specific sensing of single-stranded RNAs in human macrophages. Journal of Immunology, 9 pgs. PMID: 18250417. (link)

  4. Lee, Pui, et al. (2007). Type I interferon as a novel risk factor for endothelial progenitor cell depletion and endothelial dysfunction in systemic lupus erythematosus. Arthritis & Rheumatism, 11 pgs. PMID: 17968925. (link)

  5. Foley, et al. (2005). Roles for CXC Chemokine Ligands 10 and 11 in Recruiting CD4+ T Cells to HIV-1-Infected Monocyte-Derived Macrophage, Dendritic Cells, and Lymph Nodes. Journal of Immunology, 10 pgs. PMID: 15814716. (link)

  6. Fagnoni, et al. (2004). Reconstitution Dynamics of Plasmacytoid and Myeloid Dendritic Cell Precursors After Allogenic Myeloablative Hematopoietic Stem Cell Transplantation. Blood Journal, 10 pgs. PMID: 15010368. (link)

Documentation

Mouse MAb to Human IFN Alpha Titration in A549

Titration of Mouse MAb to Human Interferon Alpha in the A549 Cell Line

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