Anti-Human Interferon Alpha (All Subtype), Sheep Serum (PAb)

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Product Features: 
  • Sheep polyclonal antibody that neutralizes all Human IFN Alpha subtypes (IFN-alpha A, IFN-alpha 2, IFN-alpha B2, IFN-alpha C, IFN-alpha D[val114], IFN-alpha F, IFN-alpha G, IFN-alpha H2, IFN-alpha l, IFN-alpha J1, IFN-alpha K, IFN-alpha 1[Ala114], IFN-alpha 4b, IFN-alpha WA)
  • Suitable for Direct Binding ELISA

Ordering

Catalog No. Pack Size Price Quantity
31110-1

1 x 105 units

 $315.00

Specifications

Formulation Supplied frozen as neat serum diluted in phosphate buffered saline (PBS)
Antigen Mixture of recombinant human IFN alpha subtypes (IFNA2, IFNA8, IFNA10, IFNA1, IFNA21, IFNA5, IFNA14, IFNA17, IFNA7, IFNA6, IFNA4, and IFNA16)
Host Species Sheep
Bioactivity Measured by neutralization of interferon in cytopathic effect inhibition assay using A549 cells challenged with EMCV.
Storage For retention of full activity store at -70oC or below and avoid repeated freeze/thaw cycles.
Antigen Synonyms Interferon alpha, IFN alpha sheep polyclonal, IFN-a, interferon alpha sheep polyclonal, Leukocyte interferon, Leukocyte IFN, alpha interferon, interferon alfa, IFN alfa, interferon a, Type I interferon alpha, Type I IFN alpha

Tech Info / Data

Tested Applications:

  • Neutralization
  • Direct Binding ELISA

 

31110-1 Direct Binding ELISA

Direct binding assay perfomed against each human IFN alpha subtype

 

 

Refer to our Human Interferon Alpha Nomenclature Table

Citations

1 Citation:

  1. Ka, N-L., et al., (2022), "Type I IFN Stimulates IFI16-mediated aromatase expression in adipocytes that promotes E2-dependent growth of ER-positive breast cancer", Cell. Mol. Life Sci., 79(6):306, PMID: 35593921, DOI: 10.1007/s00018-022-04333-y (link)

 

References:

  1. Rubinstein, S., Familletti, P.C., and Pestka, S. (1981) "Convenient Assay for Interferons," J. Virol. 37, 755-758

  2. Familletti, P.C., Rubinstein, S., and Pestka, S. (1981) "A Convenient and Rapid Cytopathic Effect Inhibition Assay for Interferon," in Methods in Enzymology, Vol. 78 (S. Pestka, ed.), Academic Press, New York, 387-394

  3. Pestka, S. (1986) "Interferon Standards and General Abbreviations," in Methods in Enzymology (S. Pestka, ed.), Academic Press, New York 119, 14-23

Documentation

IFN Alpha Subtypes Neutralizing Activities

31110-1 Neutralizes All Human IFN Alpha Subtypes

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