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Anti-Human IFN-Alpha, Sheep Serum (PAb)

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Anti-Human IFN-Alpha, Sheep Serum (PAb)

Catalog Number: 31110

Sheep polyclonal antibody that neutralizes all Human IFN-Alpha subtypes and is suitable for Direct Binding ELISA

$345.00

Pack Size
Product Info

Specificity Binds to and blocks biological activity of all human IFN-Alpha subtypes
Tested Applications
  • Neutralization
  • Direct Binding ELISA

 

Neutralizes all Human Interferon Alpha subtypes (IFN-Alpha A, IFN-Alpha 2, IFN-Alpha B2, IFN-Alpha C, IFN-Alpha D[val114], IFN-Alpha F, IFN-Alpha G, IFN-Alpha H2, IFN-Alpha l, IFN-Alpha J1, IFN-Alpha K, IFN-Alpha 1[Ala114], IFN-Alpha 4b, IFN-Alpha WA)

Specifications

Formulation Supplied frozen as neat serum diluted in phosphate buffered saline (PBS)
Antigen Mixture of recombinant human IFN alpha subtypes (IFNA2, IFNA8, IFNA10, IFNA1, IFNA21, IFNA5, IFNA14, IFNA17, IFNA7, IFNA6, IFNA4, and IFNA16)
Host Species Sheep
Bioactivity Measured by neutralization of interferon in cytopathic effect inhibition assay using A549 cells challenged with EMCV.
Storage For retention of full activity store at -70oC or below and avoid repeated freeze/thaw cycles.
Antigen Synonyms Interferon alpha, IFN alpha sheep polyclonal, IFN-a, interferon alpha sheep polyclonal, Leukocyte interferon, Leukocyte IFN, alpha interferon, interferon alfa, IFN alfa, interferon a, Type I interferon alpha, Type I IFN alpha

Citations

1 Citation

 

  1. Ka, N-L., et al., (2022), "Type I IFN Stimulates IFI16-mediated aromatase expression in adipocytes that promotes E2-dependent growth of ER-positive breast cancer", Cell. Mol. Life Sci., 79(6):306, PMID: 35593921, DOI: 10.1007/s00018-022-04333-y (link)

 

References

 

  1. Rubinstein, S., Familletti, P.C., and Pestka, S. (1981) "Convenient Assay for Interferons," J. Virol. 37, 755-758

  2. Familletti, P.C., Rubinstein, S., and Pestka, S. (1981) "A Convenient and Rapid Cytopathic Effect Inhibition Assay for Interferon," in Methods in Enzymology, Vol. 78 (S. Pestka, ed.), Academic Press, New York, 387-394

  3. Pestka, S. (1986) "Interferon Standards and General Abbreviations," in Methods in Enzymology (S. Pestka, ed.), Academic Press, New York 119, 14-23

Documentation

Certificate of Analysis (CoA) and Safety Data Sheet (SDS)
31110-1 CoA

31110-1 Certificate of Analysis

31110 SDS

31110 Safety Data Sheet