Human Interferon Alpha D recombinant protein expressed in E.coli.
Product Info
Recombinant Human IFN-Alpha 1 (Human alpha 1; Hu-[Ala114] IFN-alpha D) obtained from human leukocyte mRNA expressed in E.coli.
IFN-Alpha 1 is one of the many interferon alpha subtypes belonging to the Type I leukocyte IFN family. The Type I IFN family has antiviral, anti-proliferative, and natural killer cell activities.
- Expression induced by viral infection
- Encoding gene IFNA1 at position Ala114
Documentation
Certificate of Analysis (CoA) and Safety Data Sheet (SDS)
11175-1 CoA
11175-1 Certificate of Analysis (CoA)
11175 SDS
11175 Safety Data Sheet
| Formulation | Supplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA) |
|---|---|
| Molecular Weight | 19.4 kDa |
| Source | cDNA obtained from human leukocyte mRNA expressed in E.coli |
| Purity | > 95% by SDS-PAGE stained by Coomassie Blue Endotoxin level < 1 EU/mg |
| Bioactivity | Measured using a cytopathic inhibition assay on Bovine Kidney Cells (MDBK) with Vesicular Stomatis Virus (VSV); human lung carcinoma cell line A549 with encephalomyocarditis virus (EMCV) |
| Storage | For retention of full activity store at -70 ºC or below and avoid repeated freeze-thaw cycles |
| Synonyms | Hu-[Ala114] IFN-αD |
| Accession Number | J00210 |
Application Note
- A Comparison of the Binding of IFN-Alpha Subtypes to Isolated IFNAR1 and IFNAR2 with Activity in Antiviral and Antiproliferative Assays (link)