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Human IFN-Alpha 8 (Alpha B2) Protein

Hero Region

Human IFN-Alpha 8 (Alpha B2) Protein

Catalog Number: 11115

Human Interferon Alpha 8 recombinant protein expressed in E.coli. (Pack Size: 1 x 10⁵ units)


Pack Size
Product Info

Recombinant Human IFN-Alpha B2 (alpha 8) obtained from human leukocyte mRNA expressed in E.coli.


IFN-Alpha 8 is one of the many interferon alpha subtypes belonging to the Type I leukocyte IFN family. The Type I IFN family has antiviral, anti-proliferative, and natural killer cell activities.


  • Expression induced by viral infection
  • Encoding gene IFNA8


Formulation Supplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA)
Molecular Weight 19.5 kDa
Source cDNA obtained from human leukocyte mRNA expressed in E.coli
Purity > 95% by SDS-PAGE stained by Coomassie Blue 
Bioactivity Measured using a cytopathic inhibition assay on Bovine Kidney Cells (MDBK) with Vesicular Stomatis Virus (VSV); human lung carcinoma cell line A549 with encephalomyocarditis virus (EMCV)
Storage For retention of full activity store at -70 ºC or below and avoid repeated freeze-thaw cycles
Synonyms Hu-IFN-α8
Accession Number X03125

Tech Info & Data

Application Note


  • A Comparison of the Binding of Interferon Alpha Subtypes to Isolated IFNAR1 and IFNAR2 with Activity in Antiviral and Antiproliferative Assays (link)


6 Citations


  1. Li, Y.,et al., (2023), "An Extracellular Humanized IFNAR Immunocompetent Mouse Model for Analyses of Human Interferon Alpha and Subtypes", Emerg Microbes Infect. 2287681. PMID: 37994664, DOI: 10.1080/22221751.2023.2287681 (link)

  2. Liu, Qiuzhen, et al. (2014). Melanoma NOS1 expression promotes dysfunctional IFN signaling. JCI, 13 pgs. PMID: 24691438. (link)

  3. Rompaey, Luc Van, et al. (2013). Preclinical Characterization of GLPG0634, a Selective Inhibitor of JAK1, for the Treatment of Inflammatory Diseases. Journal of Immunology, 11 pgs. PMID: 24006460. (link)

  4. Wilson, Timothy R, et al. (2012). Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature, 12 pgs. PMID: 22763448. (link)

  5. Kang, Dong-Chul, et al. (2004). Expression Analysis and Genomic Characterization of Human Melanoma Differentiation Associated Gene-5, mda-5: a Novel Type I Interferon-Responsive Apoptosis-Inducing Gene. Oncogene, 12 pgs. PMID: 14676839. (link)

  6. Yanai, Yoshiaki, et al. (2001). Characterization of the antitumor activities of IFN-alpha8 on renal cell carcinoma cells in vitro. Journal of Interferon & Cytokine Research, 8 pgs. PMID: 11798471. (link)


Certificate of Analysis (CoA) and Safety Data Sheet (SDS)
11115 SDS

11115 Safety Data Sheet

11115-1 CoA

11115-1 Certificate of Analysis (CoA)