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Mouse IFN-Alpha 13

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Mouse IFN-Alpha 13

Catalog Number: 12130

Recombinant Mouse Interferon Alpha 13 protein expressed in E.coli. Member of the Mouse IFN-Alpha family which may be constitutively expressed and thus have different expression criteria than other subtypes.

$365.00

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Product Info

Mouse IFN-Alpha 13 is a new interferon which may be constitutively expressed and thus have different expression criteria than other Mu IFN-Alpha subtypes.

Specifications

Formulation Supplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA)
Molecular Weight 19.1 kDa
Source cDNA obtained from mouse leukocyte interferon expressed in E.coli
Purity > 95% by SDS-PAGE stained by Coomassie Blue
Endotoxin level < 1 EU/μg
Bioactivity Measured using a cytopathic inhibition assay on Mouse (L929) cells with EMCV.
The EC50 for IFN in this assay is ~ 5 U/ml.
Storage For retention of full activity store at -70°C or below and avoid repeated freeze/thaw cycles
Synonyms Mu IFN-α13, Mouse IFN Alpha Subtype, Mouse IFN Protein Subtype, Interferon Alpha, IFN Alpha, IFN-a, Type I IFN Alpha
Accession Number AY220461

Tech Info & Data

Background

 

Mouse IFN-Alpha 13 was recently cloned from cells infected with Theiler's virus [van Pesch and Michiels (2003) J. Biol. Chem., 278(47):46321] and from genomic DNA [Hardy et al. (2004) Genomics 84(2):331]. Van Pesch and Michiels had suggested that Mouse IFN Alpha 13 is expressed constitutively in L929 cells. They have also shown that priming of the cells with IFN alpha/beta leads to a decrease in this transcript.

 

Summary: Mouse IFN-Alpha 13 is a new interferon which may be constitutively expressed and thus have different expression criteria than other Mu IFN-Alpha subtypes.

 

For more information on Mouse IFN-Alpha subtype nomenclature click here.

Citations

References 

 

  1. van Pesch and Michiels (2003) J. Biol. Chem. 278 (47):46321.

  2. Hardy et al. (2004) Genomics 84(2):331.

Documentation

Certificate of Analysis (CoA) and Safety Data Sheet (SDS)
12130-1 CoA

12130-1 Certificate of Analysis (CoA)

12130 SDS

12130 Safety Data Sheet